Special Issue "Immunoglobulin"
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: closed (31 October 2014)
Prof. Rhodri Ceredig
Bioscience Building, Corrib Village, National University of Ireland, Galway, Ireland
Interests: mouse lymphocyte development; Interleukin-7; cell lineage decisions in hematopoiesis; mesenchymal stromal cells
Immunoglobulin, the secreted form of the B lymphocyte receptor molecule, represents one of nature’s most flexible and potent biomolecules. Two functions (i.e., highly specific recognition and effector functions) are combined into one molecule. The specific molecular interaction between the antibody paratope and its corresponding antigen epitope activates the effector function of the molecule, thereby linking the exquisite specificity of the adaptive immune system with the prototypic cellular and molecular components of the natural immune response. With current molecular biological techniques, these two immunoglobulin functions can be independently manipulated. Intensive analysis of B lymphocyte responses has uncovered details concerning immunoglobulin class switching and somatic hypermutation during T dependent antibody responses. For readers of Biomolecules, this Special Issue provides an up-to-date account of some of the more intriguing aspects of immunoglobulins.
Prof. Rhodri Ceredig
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 600 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.