Special Issue "Gene Expression and Regulation"

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A special issue of Biology (ISSN 2079-7737).

Deadline for manuscript submissions: closed (31 October 2012)

Special Issue Editor

Guest Editor
Dr. Mary O'Connell
Medical Research Council, Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, Scotland, UK
Website: http://www.hgu.mrc.ac.uk/people/m.oconnell.html
E-Mail: M.OConnell@hgu.mrc.ac.uk
Interests: RNA editing; RNA Protein interaction; RNA interference

Special Issue Information

Dear Colleagues,

Gene expression and how it is regulated is a fundamental question in biology and therefore its complexity is not surprising. Initially the major focus of research was on transcription factors as the major modulators of gene expression. Then enhancers and enhancer binding proteins were found to be critical for gene expression. In recent years epigenetic changes such as DNA methylation and histone methylation have added layers of complexity as they also regulate gene expression. Long range DNA looping can also influence gene expression as it brings promoters and enhancers proximal to genes. With the availability of high throughput sequencing profiling of gene expression in different tissues and also in different diseases has become a very active area of research. What has become a major challenge is to draw a coherent picture from a large volume of data, of what are key regulators of gene expression. This special issue will cover original research papers on this very broad topic. The submission of reviews is also welcomed.

Dr. Mary O'Connell
Guest Editor

Keywords

  • transcription factors
  • enhancers
  • enhancer binding proteins
  • DNA methylation
  • histone methylation
  • DNA looping
  • expression profiling
  • miRNA and post-translational gene silencing
  • asymmetrical distribution of genetic factors

Published Papers (13 papers)

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p. 976-1033
by  and
Biology 2013, 2(3), 976-1033; doi:10.3390/biology2030976
Received: 15 May 2013; in revised form: 13 June 2013 / Accepted: 20 June 2013 / Published: 9 July 2013
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(This article belongs to the Special Issue Gene Expression and Regulation)
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p. 861-871
by , , , , , , , ,  and
Biology 2013, 2(3), 861-871; doi:10.3390/biology2030861
Received: 11 April 2013; in revised form: 13 May 2013 / Accepted: 15 May 2013 / Published: 28 June 2013
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(This article belongs to the Special Issue Gene Expression and Regulation)
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p. 555-586
by  and
Biology 2013, 2(2), 555-586; doi:10.3390/biology2020555
Received: 25 January 2013; in revised form: 1 March 2013 / Accepted: 6 March 2013 / Published: 28 March 2013
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(This article belongs to the Special Issue Gene Expression and Regulation)
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p. 341-355
by , , , , ,  and
Biology 2013, 2(1), 341-355; doi:10.3390/biology2010341
Received: 24 December 2012; in revised form: 24 December 2012 / Accepted: 29 January 2013 / Published: 28 February 2013
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(This article belongs to the Special Issue Gene Expression and Regulation)
p. 233-283
by
Biology 2013, 2(1), 233-283; doi:10.3390/biology2010233
Received: 25 December 2012; in revised form: 15 January 2013 / Accepted: 15 January 2013 / Published: 25 January 2013
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(This article belongs to the Special Issue Gene Expression and Regulation)
p. 107-141
by , ,  and
Biology 2013, 2(1), 107-141; doi:10.3390/biology2010107
Received: 5 November 2012; in revised form: 27 December 2012 / Accepted: 5 January 2013 / Published: 14 January 2013
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(This article belongs to the Special Issue Gene Expression and Regulation)
p. 64-84
by ,  and
Biology 2013, 2(1), 64-84; doi:10.3390/biology2010064
Received: 1 November 2012; in revised form: 21 December 2012 / Accepted: 4 January 2013 / Published: 9 January 2013
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(This article belongs to the Special Issue Gene Expression and Regulation)
p. 26-39
by , , ,  and
Biology 2013, 2(1), 26-39; doi:10.3390/biology2010026
Received: 31 October 2012; in revised form: 1 December 2012 / Accepted: 14 December 2012 / Published: 27 December 2012
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(This article belongs to the Special Issue Gene Expression and Regulation)
p. 869-879
by  and
Biology 2012, 1(3), 869-879; doi:10.3390/biology1030869
Received: 7 October 2012; in revised form: 27 November 2012 / Accepted: 3 December 2012 / Published: 13 December 2012
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(This article belongs to the Special Issue Gene Expression and Regulation)
p. 778-793
by , , ,  and
Biology 2012, 1(3), 778-793; doi:10.3390/biology1030778
Received: 1 November 2012; in revised form: 21 November 2012 / Accepted: 21 November 2012 / Published: 5 December 2012
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(This article belongs to the Special Issue Gene Expression and Regulation)
p. 698-713
by  and
Biology 2012, 1(3), 698-713; doi:10.3390/biology1030698
Received: 25 September 2012; in revised form: 31 October 2012 / Accepted: 16 November 2012 / Published: 22 November 2012
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p. 714-735
by , , , ,  and
Biology 2012, 1(3), 714-735; doi:10.3390/biology1030714
Received: 17 October 2012; in revised form: 6 November 2012 / Accepted: 9 November 2012 / Published: 22 November 2012
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(This article belongs to the Special Issue Gene Expression and Regulation)
p. 557-574
by  and
Biology 2012, 1(3), 557-574; doi:10.3390/biology1030557
Received: 9 July 2012; in revised form: 30 August 2012 / Accepted: 9 October 2012 / Published: 25 October 2012
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Last update: 25 February 2014

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