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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Progression of the Immune Escape Mechanism in Tumors

edited by

Sumit Mukherjee

and

Sheila Spada

submission deadline 30 Sep 2024 | 4 articles | Viewed by 31550 | Submission Open

Keywords: cancer immunology; immune checkpoints; cancer immunotherapy; cancer immune escape ; Immuno-oncology; CAR T cells

(This special issue belongs to the Section Cancer Biology)

Mesenchymal Stem Cells: What We Have Learned and How to Manage Them

edited by

Nadia Lampiasi

submission deadline 30 Sep 2024 | 11 articles | Viewed by 28300 | Submission Open

Keywords: mesenchymal stem cells; secretomes; migrasomes; miRNAs; senescence; cell renewal; regenerative medicine

(This special issue belongs to the Section Cell Biology)

Immune Response Regulation in Animals

edited by

Rong Gao

and

Hua-Ji Qiu

submission deadline 30 Sep 2024 | 8 articles | Viewed by 16231 | Submission Open

Keywords: immunoregulation of animals; vaccination; immunomodulators; immune memory; cytokine; biotechnology; immune response; molecular networks

(This special issue belongs to the Section Immunology)

Musculoskeletal Biology: Impact of Ageing and Disease

edited by

Rachel A. Oldershaw

and Anne McArdle

submission deadline 30 Sep 2024 | 4 articles | Viewed by 9045 | Submission Open

Keywords: musculoskeletal system; joint; chronic disease; frailty; ageing

(This special issue belongs to the Section Physiology)

Pathogenic Factors and Key Pathways of Metabolic Diseases

edited by Aijun Qiao

submission deadline 30 Sep 2024 | 3 articles | Viewed by 8037 | Submission Open

Keywords: metabolism diseases; lipid overload; insulin resistance; pathogenic molecules; biomarkers; drug therapy

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Molecular Mechanism of Three-Dimensional Genome Organization and Gene Regulation

edited by

and

submission deadline 30 Sep 2024 | 2 articles | Viewed by 5396 | Submission Open

Keywords: 3D genome; enhancer-promoter communication; DNA loop extrusion; cohesin; TADs; contact domains; chromatin loops; A/B compartments; subcompartments; CTCF

(This special issue belongs to the Section Genetics and Genomics)

β-Cells at the Center of Type 1 and Type 2 Diabetes

edited by

Jeffery S. Tessem

submission deadline 30 Sep 2024 | 3 articles | Viewed by 5066 | Submission Open

Keywords: beta cell; insulin secretion; cell cycle; mitochondrial respiration; nuclear hormone receptors; Nr4a1; Nr4a3

Microglial Cells in Neurodegenerative Diseases

edited by

Björn Spittau

submission deadline 30 Sep 2024 | 1 articles | Viewed by 3594 | Submission Open

Keywords: Microglia ; Neurodegenerative diseases ; Disease-associated microglia (DAM) ; Microglia activation ; Alzheimer's disease ; Parkinson's disease ; Ischemic stroke

(This special issue belongs to the Section Neuroscience)

Extracellular Vesicles: Multifaceted Biological Nanoparticles in Health and Disease (Volume II)

edited by

Meena Kumari

submission deadline 30 Sep 2024 | 1 articles | Viewed by 3203 | Submission Open

Keywords: extracellular vesicles and exosomes; isolation and characterization; biological activity in development; differentiation; health and disease; therapeutic applications

(This special issue belongs to the Section Cell Biology)

Uncovering the Mechanisms of Plant Salinity Stress Response and Tolerance

edited by

Ricardo Aroca

submission deadline 30 Sep 2024 | 2 articles | Viewed by 2570 | Submission Open

Keywords: genetic resources; ion toxicity; molecular signalling; nutrient uptake; plant hormones; soil beneficial microorganisms; water relations

(This special issue belongs to the Section Plant Science)

Metallo-Enzymes as Drug Targets

edited by

Giuseppina De Simone

Martina Buonanno

and

Simona Maria Monti

submission deadline 30 Sep 2024 | 1 articles | Viewed by 2417 | Submission Open

Keywords: metalloenzyme; drug design; anticancer drug; antibacterial drug; drug target

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Host–Pathogen Interactions and Pathogenesis

edited by

Sashi Kant

, Deeksha Tripathi and Saurabh Pandey

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1926 | Submission Open

Keywords: host-pathogen dynamics; infectious disease mechanisms; virulence factors; microbial interactions; pathogenicity; emerging pathogens; immunological response; immunomodulation tactics; infection prevention; disease pathophysiology

Unveiling Disease Molecular Signaling Pathways: Targeted Drug Discoveries for Pathway Modulation

edited by Stephen P. Wren

submission deadline 30 Sep 2024 | Viewed by 359 | Submission Open

Keywords: signaling molecules; disease mechanisms and pathways; small-molecule therapeutics

(This special issue belongs to the Section Medical Biology)

Pathogenic Mechanisms of Hypertension and Neurodegenerative Disorders

edited by

Yansheng Du

and

Mingming Chen

submission deadline 30 Sep 2024 | Viewed by 321 | Submission Open

Keywords: neurodegenerative diseases; hypertension; stroke; dementia; cerebral vasculature; hypoperfusion; inflammation; microglia; astrocytes; neurons

(This special issue belongs to the Section Neuroscience)

Unraveling the Complexities of Aging: Inflammation, Immunosenescence, and Aging

edited by

Sylvia L. F. Pender

submission deadline 30 Sep 2024 | Viewed by 293 | Submission Open

Keywords: immunosenescence; chronic inflammation; aging; age-related diseases; immune system; regenerate

(This special issue belongs to the Section Immunology)

Mining Favorable Alleles for Crop Yield, Biotic and Abiotic Stress Tolerance

edited by

Jianlong Xu

and

Meixue Zhou

submission deadline 1 Oct 2024 | 5 articles | Viewed by 4778 | Submission Open

Keywords: high yield; biotic and abiotic stress tolerance; favorable gene editing; favorable gene transformation; genomic selection; favorable allele or haplotype identification; pyramiding breeding by molecular technology

(This special issue belongs to the Section Plant Science)

Role of Plant-Fungi Interactions in Nutrient Cycling and Ecosystem Functioning

edited by Yonggang Wang

submission deadline 1 Oct 2024 | 1 articles | Viewed by 938 | Submission Open

Keywords: plant-fungi interactions; mycorrhizal associations; nutrient cycling; ecosystem functioning; decomposition processes; climate change; sustainable agriculture; microbial communities; restoration ecology; endophytic fungi

(This special issue belongs to the Section Plant Science)

Genomic Features and Potential Applications in Sarcomas

edited by Liangliang Wang

submission deadline 4 Oct 2024 | Viewed by 142 | Submission Open

Keywords: sarcomas; genetic heterogeneity; comprehensive genomic characterization; therapeutic target; treatment strategy; biomarkers

Biological Rhythms and Molecular Clockworks in Physiology and Pathology

edited by

Gianluigi Ubaldo Mazzoccoli

and

Marina Maria Bellet

submission deadline 19 Oct 2024 | 7 articles | Viewed by 16360 | Submission Open

Keywords: biological rhythms; molecular clockworks; circadian timing system; circadian desynchrony; circadian disruption; chronopathology; chronopharmacology and chronotherapeutics; chronomedicine

(This special issue belongs to the Section Physiology)

Applications of Stable Isotope Analysis in Ecology

edited by

Edoardo Calizza

Giulio Careddu

and

Maria Letizia Costantini

submission deadline 31 Oct 2024 | 7 articles | Viewed by 21628 | Submission Open

Keywords: community ecology; population ecology; biotic interactions; food webs; nutrient cycling; ecosystem structure and functioning; disturbance; stability; environmental change; climate change; invasive species

(This special issue belongs to the Section Ecology)

Advances in the Fields of Neurotrauma and Neuroregeneration

edited by

Alexander Younsi

Guoli Zheng

and

Xing Cheng

submission deadline 31 Oct 2024 | 6 articles | Viewed by 19598 | Submission Open

Keywords: neurotrauma; spinal cord injury; traumatic brain injury; neuropathic pain; neuroinflammation; axonal regeneration; postinjury plasticity; neurorehabilitation; cell transplantation

(This special issue belongs to the Section Neuroscience)

Coping with Temperature Increase Induced by Climate Warming: Trends in Ectothermic Species

edited by

Andreas Walzer

submission deadline 31 Oct 2024 | 8 articles | Viewed by 18104 | Submission Open

Keywords: biodiversity; climate warming; ectothermic species; geographic ranges; heat waves; evolutionary adaptations; phenotypic plasticity; species interactions; thermal acclimation

Infectious Diseases in Aquaculture: Mechanisms, Detection, and Control

edited by

Jie Huang

and

Changming Bai

submission deadline 31 Oct 2024 | 6 articles | Viewed by 12789 | Submission Open

Keywords: aquaculture; emerging diseases; industry loss; mass mortality; detection; epidemiology

(This special issue belongs to the Section Zoology)

Editorial Board Members’ Collection Series: Pathology of Cancer and Cardiovascular Disease

edited by

Mridula Chopra

Helen L. Fillmore

and

Maurizio Forte

submission deadline 31 Oct 2024 | 2 articles | Viewed by 3215 | Submission Open

Keywords: cancer; cardiovascular disease; biomarkers; gut microbiome; inflammation; health policy; diet and lifestyle

Multi-omics in Oncology: Discovering Novel Biomarkers and Targets

edited by

Chia-Jung Li

submission deadline 31 Oct 2024 | 1 articles | Viewed by 2833 | Submission Open

Keywords: multi-omics; cancer signaling; biomarkers

(This special issue belongs to the Section Cancer Biology)

Genetic and Epigenetic Mechanisms of Longevity and Aging, Volume II

edited by

Michela Borghesan

and Pilar Picallos-Rabina

submission deadline 31 Oct 2024 | 1 articles | Viewed by 2458 | Submission Open

Keywords: genetics of aging; cellular aging; gene regulation; genetic mechanisms of longevity; gene expression; genetic modulation; healthy aging; age-related pathologies; genetics of longevity; epigenetic of longevity; epigenetic of aging

Recent Advances in Molecular Allergology

edited by

Marianne Raith

submission deadline 31 Oct 2024 | 1 articles | Viewed by 2322 | Submission Open

Keywords: allergen identification; allergen characterization; cross-reactive allergens; allergen immunotherapy; IgE-binding epitopes; T-cell epitopes; allergen modification

(This special issue belongs to the Section Immunology)

Animal Models for Disease Mechanisms

edited by

Isabel R. Dias

submission deadline 31 Oct 2024 | 2 articles | Viewed by 2234 | Submission Open

Keywords: animal models; spontaneous models; induced models; disease mechanisms; pathogenesis research

(This special issue belongs to the Section Zoology)

Mechanisms of Sex Determination and Gonad Development

edited by Rafal P. Piprek

submission deadline 31 Oct 2024 | 1 articles | Viewed by 2126 | Submission Open

Keywords: sex determination; sex differentiation; development; gonad; testis; ovary; genes; sex chromosomes; sex hormones; hermaphroditism

(This special issue belongs to the Section Developmental Biology)

Application of Bioinformatics to Unravel the Molecular Mechanisms of Cancer Biology

edited by

Yuanyan Xiong

submission deadline 31 Oct 2024 | 1 articles | Viewed by 1468 | Submission Open

Keywords: cancer biology; bioinformatics; genetics; epigenetics; transcriptomics

(This special issue belongs to the Section Biochemistry and Molecular Biology)

2nd Edition: Macro-Ecology, Macro-Evolution and Conservation of Animals and Plants

edited by

Youhua Chen

submission deadline 31 Oct 2024 | 1 articles | Viewed by 968 | Submission Open

Keywords: biodiversity conservation; global change biology; plant ecology; animal ecology; geographic information system; macro-genetics

(This special issue belongs to the Section Evolutionary Biology)

Discovering the Physiological Significance and Regulatory Mechanisms of Circadian Rhythm Generation

edited by Xiaodong Li

submission deadline 31 Oct 2024 | Viewed by 522 | Submission Open

Keywords: circadian rhythms; biological clocks; chromatin; transcription; histone; nucleosome; pausing; pause release

(This special issue belongs to the Section Genetics and Genomics)

Regulation and Plasticity in Autonomic Pathways

edited by

Chao-Yin Chen

, Christopher G. Wilson and

Yumei Feng Earley

submission deadline 31 Oct 2024 | Viewed by 487 | Submission Open

Keywords: cardiovascular; metabolic; respiratory; neuroplasticity; autonomic regulation

(This special issue belongs to the Section Neuroscience)

Epigenetics and Functional Studies of Neurodevelopmental Disorders

edited by

Carla Lintas

and

Claudio Tabolacci

submission deadline 31 Oct 2024 | Viewed by 401 | Submission Open

Keywords: neurodevolpmental disorders; epigenetics; natural compounds; inflammation; immune system; environmental factors; exposome

(This special issue belongs to the Section Genetics and Genomics)

Understanding the Molecular Basis of Genetic Dental Diseases

edited by Yuta Chiba

submission deadline 31 Oct 2024 | Viewed by 262 | Submission Open

Keywords: genetic diseases; dental anomaly; genetic abnormality related to dental diseases; tooth development; molecular biology of tooth development

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Application and Mechanism of Marine Bioactive Substances in Animal Nutrition

edited by

Wen-Chao Liu

submission deadline 1 Nov 2024 | 2 articles | Viewed by 3457 | Submission Open

Keywords: marine polysaccharides; marine polyphenols; marine antioxidants; marine immunomodulators; seaweeds; animals

(This special issue belongs to the Section Marine Biology)

Human Leukocyte Antigen (HLA)—Antigen Interactions in Vaccine Development

edited by

Apostolos P. Georgopoulos

submission deadline 12 Nov 2024 | 2 articles | Viewed by 1696 | Submission Open

Keywords: HLA; vaccine; antigen; antibody; cancer; binding affinity; biophysical modeling; lymphocytes

Lysosomes and Diseases Associated with Its Dysfunction

edited by

Sokhna M.S. Yakhine-Diop

submission deadline 15 Nov 2024 | 3 articles | Viewed by 8604 | Submission Open

Keywords: activities; mutations; endocytosis; autophagy; metabolism; proteins

(This special issue belongs to the Section Cell Biology)

Multidisciplinary Insights on Bone Healing (Volume II)

edited by

Alexandre Anesi

and

Mattia Di Bartolomeo

submission deadline 17 Nov 2024 | 11 articles | Viewed by 28041 | Submission Open

Keywords: bone healing; bone regeneration; bone diseases and related pathologies; bone tissue engineering; bone substitute

Unique Response of Pluripotent Stem Cells to External Stimuli and Stresses

edited by

Taku Kaitsuka

Farzana Hakim

and

Mohd. Raeed Jamiruddin

submission deadline 17 Nov 2024 | 4 articles | Viewed by 6803 | Submission Open

Keywords: stem cells; stress response; differentiation; heat stress; hypoxic stress; oxidative stress; proteotoxic stress

(This special issue belongs to the Section Cell Biology)

Cell Self-Destruction (Programmed Cell Death), Immunonutrition and Metabolism

edited by

Huashan Shi

and

Vishwanath Venketaraman

submission deadline 30 Nov 2024 | 12 articles | Viewed by 33877 | Submission Open

Keywords: autoimmunity; cell self-destruction; infection; inflammation; immunonutrition; lipotoxicity; metabolism; programmed cell death

(This special issue belongs to the Section Immunology)

Mitochondria: The Diseases' Cause and Cure

edited by

Susana P. Pereira

and Ludgero C. Tavares

submission deadline 30 Nov 2024 | 9 articles | Viewed by 21763 | Submission Open

Keywords: pathology and clinical aspects of mitochondrial diseases; mitochondrial biology; metabolism; bioenergetic; biochemistry; energy production; disease; treatment; prevention; pharmacology

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Epigenetic Modifications and Changes in Neurodegenerative Diseases

edited by

Andrea Stoccoro

submission deadline 30 Nov 2024 | 5 articles | Viewed by 13772 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; amyotrophic lateral sclerosis; epigenetics; DNA methylation; histone tail modifications; non-coding RNAs; biomarkers; environmental epigenetics

(This special issue belongs to the Section Neuroscience)

Conservation Genetics as a Management Tool for Endangered, Vulnerable, and Threatened Species

edited by

Claudia Greco

Daniela Pacifico

and

Irene Pellegrino

submission deadline 30 Nov 2024 | 7 articles | Viewed by 13559 | Submission Open

Keywords: conservation genetics; forensics; molecular markers; management; plants; animals

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Maternal Adaptation in Physiological and Pathological Pregnancy

edited by

Qi Chen

and

Yunhui Tang

submission deadline 30 Nov 2024 | 5 articles | Viewed by 10945 | Submission Open

Keywords: pregnancy; maternal adaptation; placenta; cardiovascular system; immune system; complications of pregnancy

(This special issue belongs to the Section Reproductive Biology)

Biological Response of Plants to Environmental Changes

edited by

Stefano Loppi

and

Luca Paoli

submission deadline 30 Nov 2024 | 7 articles | Viewed by 10417 | Submission Open

Keywords: air pollution; biological effects; biomonitoring; climate change; global change; plants

(This special issue belongs to the Section Plant Science)

The Convergence of Neuroscience and ICT: From Data to Insights

edited by

Daniele Giansanti

submission deadline 30 Nov 2024 | 2 articles | Viewed by 7863 | Submission Open

Keywords: neuroscience; neurobiology; neuroimaging; ICT; digitalization; brain; behavior; cognitive control; brain imaging; computational neuroscience

(This special issue belongs to the Section Neuroscience)

Alien Marine Species in the Mediterranean Sea

edited by

Claudia Cosentino

submission deadline 30 Nov 2024 | 3 articles | Viewed by 6279 | Submission Open

Keywords: marine organisms; ecology and paleoecology; biodiversity; Mediterranean ecosystem

(This special issue belongs to the Section Marine Biology)

Dendrochronology in Arid and Semiarid Regions

edited by

Zongshan Li

submission deadline 30 Nov 2024 | 4 articles | Viewed by 5135 | Submission Open

Keywords: tree rings; growth– climate response; dendrochronology; dendroecology; dryland regions

(This special issue belongs to the Section Ecology)

Recent Advances in Wolbachia and Spiroplasma Symbiosis

edited by

Bamisope Steve Bamisile

Mubasher Hussain

and

Junaid Ali Siddiqui

submission deadline 30 Nov 2024 | 2 articles | Viewed by 4851 | Submission Open

Keywords: herbivore-associated bacterial symbionts; facultative endosymbionts; co-infection; cytoplasmic incompatibility; complex relationship; horizontal transmission; host-insects; physiological interactions; intracellular bacteria

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