Special Issue "Synergisms of Agricultural Bioactive Compounds to Prevent Disease"


A special issue of Agriculture (ISSN 2077-0472).

Deadline for manuscript submissions: closed (20 March 2015)

Special Issue Editor

Guest Editor
Dr Vicki L. Schlegel
Department of Food Science and Technology, 143 Filley Hall—East Campus, University of Nebraska-Lincoln, Lincoln, NE 68583, USA
Phone: 416-0294

Special Issue Information

Dear Colleagues,

Natural product consumption has been associated to lower risks of multiple chronic diseases, with secondary phytochemicals (phenols, flavonoids, anthocyanins, alkaloids, isothiocyanates) and other small molecular weight molecules (fatty acids, sterols, amino acids, and organic acids, etc.) playing a significant role. The diverse mixture of phytochemicals present in whole foods may act through either additive or synergistic mechanisms to impart a greater biologic effect than is elicited by any one component in isolation. Moreover, the unique combinations of these components may also affect functional qualities of the end product. Therefore, this Special Issue of Agriculture will be dedicated to the additive/synergistic benefits of dietary bioactives in terms of their ability to remediate or prevent cellular stresses (oxidation/inflammation), infections, or various diseases. Mechanistic type manuscripts showing the potential and multiple targets of these active additives/synergists are highly encouraged. Manuscripts that describe the development of novel methodologies for analyzing synergistic interactions of dietary bioactives, that demonstrate the effects of dietary bioactive synergists on food functionality when used as food additives to other matrices, or that report on unique delivery systems for the dietary synergists are also welcome.

Dr. Vicki L. Schlegel
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Agriculture is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 300 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.


  • dietary bioactives
  • phytochemicals
  • synergists
  • additives
  • human health

Published Papers

No papers have been published in this special issue yet.

Last update: 14 April 2015

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