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M103
Received: 18 August 1999 / Accepted: 28 August 1999 / Published: 8 October 1999
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M104
Received: 28 August 1999 / Accepted: 7 September 1999 / Published: 8 October 1999
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M105
Received: 28 August 1998 / Accepted: 1 September 1999 / Published: 8 October 1999
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M106
Received: 28 August 1999 / Accepted: 2 September 1999 / Published: 8 October 1999
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M107
Received: 28 August 1999 / Accepted: 2 September 1999 / Published: 8 October 1999
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M108
Received: 25 August 1999 / Accepted: 8 September 1999 / Published: 8 October 1999
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M109
Received: 25 August 1999 / Accepted: 8 September 1999 / Published: 8 October 1999
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M110
Received: 13 September 1999 / Accepted: 20 September 1999 / Published: 8 October 1999
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M111
Received: 13 September 1999 / Accepted: 20 September 1999 / Published: 8 October 1999
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M112
Received: 13 September 1999 / Accepted: 20 September 1999 / Published: 8 October 1999
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M113
Received: 13 September 1999 / Accepted: 20 September 1999 / Published: 8 October 1999
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M114
Received: 15 September 1999 / Accepted: 15 September 1999 / Published: 8 October 1999
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M115
Received: 15 September 1999 / Accepted: 15 September 1999 / Published: 8 October 1999
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p. 264-271
Received: 4 June 1999 / Accepted: 10 August 1999 / Published: 6 September 1999
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| Download PDF Full-text (74 KB) Abstract: Substitution of 4-methyl-[1,8]-naphthyridine in 2 and 7 position by alkylamines leads to highly fluorescent compounds. The arrangement of hydrogen donor and acceptor groups of these naphthyridines allows interactions with guanine and guanine cytosine base pairs. The described synthesis offers easy access to these small and stable fluorescent probes.
p. 272-278
Received: 21 June 1999 / Accepted: 20 July 1999 / Published: 12 September 1999
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| Download PDF Full-text (42 KB) Abstract: The thermal and acid-catalyzed intramolecular rearrangement of the (Z)- and (E)-cyclodecene-1,4-dione compounds deriving from steroids, 2a,b and 3a,b, respectively, proceeds stereoselectively to give the corresponding configurationally different spiro-γ-lactone derivatives, the (5R,9R)-isomers 4a,b (from the (Z)-cyclodecenediones 2a,b) and the (5R,9S)-isomers 5a,b (from the (E)-cyclodecenediones 3a,b). The semiempirical MNDOAM1 and PM3 molecular orbital methods were applied to elucidate the possible mechanistic pathway of the observed intramolecular process leading to the spiro-γ-lactone structures.
p. 279-286
Received: 20 August 1999 / Accepted: 7 September 1999 / Published: 22 September 1999
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| Download PDF Full-text (46 KB) Abstract: The title 3-amino-2-thiohydantoins 3 has been prepared in very good yields by the reaction of alkyl isothiocynatocarboxylates 1 with hydrazine hydrate.The synthesis of starting isothiocyanates as well as spectral data of 3-aminothiohydantoins and alkyl isothiocyanatocarboxylates has been presented.
p. 287-309
Received: 23 February 1999 / Accepted: 4 June 1999 / Published: 25 September 1999
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| Download PDF Full-text (136 KB) Abstract: Synthesis of purines and purine mono-1-oxides from the respective 5-substituted 4-nitroimidazole derivatives is described. The commercially available 4-nitroimidazole, in a few simple steps (including Vicarious Nucleophilic Substitution of Hydrogen), was transformed into: 4-aminoimidazoyl-5-carboximes, N -[1-(4-amino-1H -imidazol-5-yl)methylidene]-N -(aryl)amine derivatives or into 4-amino-5-aminomethyl-imidazole. These intermediates were cyclized to the final products.
p. 310-315
Received: 22 August 1999 / Accepted: 12 September 1999 / Published: 10 October 1999
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| Download PDF Full-text (31 KB) Abstract: Trimethylsilyl enol ethers of 1,3-diketones are generated “in situ” or obtained in high isolated yield by the reaction of 1,3-diketones with trimethylcyanosilane in various solvents such as cyclohexane, hexane, benzene, methylene chloride, chloroform, carbon tetrachloride, and acetonitrile.
p. 316-317
Received: 30 September 1999 / Published: 31 October 1999
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p. 318-319
Received: 7 September 1999 / Published: 31 October 1999
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