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M116
Received: 18 September 1999 / Accepted: 4 October 1999 / Published: 23 November 1999
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M117
Received: 17 September 1999 / Accepted: 4 October 1999 / Published: 23 November 1999
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M118
Received: 17 September 1999 / Accepted: 4 October 1999 / Published: 23 November 1999
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M119
Received: 13 October 1999 / Accepted: 14 October 1999 / Published: 23 November 1999
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M120
Received: 13 October 1999 / Accepted: 14 October 1999 / Published: 23 November 1999
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M121
Short Note:
3a,4,5,6,7,8,9,10,11,12,13,13a-Dodecahydro-3-(4-chlorophenyl)cyclododeca[d]isoxazole
Received: 22 October 1999 / Accepted: 1 November 1999 / Published: 23 November 1999
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M122
Received: 22 October 1999 / Accepted: 1 November 1999 / Published: 23 November 1999
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M123
Received: 22 October 1999 / Accepted: 1 November 1999 / Published: 23 November 1999
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M124
Received: 22 October 1999 / Accepted: 1 November 1999 / Published: 23 November 1999
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p. 320-328
Received: 25 August 1999 / Accepted: 12 September 1999 / Published: 26 October 1999
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| Download PDF Full-text (61 KB) Abstract: 17 O NMR spectra of RCOX (R = Me, Ph), RCH=CHCOX (R = H, Ph, Me, CO2 Et) and Me2 C=CHCOX (X = H, Me, Et, i-Pr, t-Bu, Ph, PhCH=CH, OMe, OEt, Cl, CN, CF3 , CO2 Et) are reported. The 17 O shift values of these carbonyl compounds depend mainly on the electron donating power of X and correlate well with the resonance constants sR + of X. This suggests that the d(17 O) values can be used to reflect qualitatively the electrophilicity of the carbonyl group. The shielding effect of the substituent R in RCH=CHCOX is diminished with increasing the electronic donating power of X and correlates with s+ values of X.
p. 329-332
Received: 13 August 1999 / Accepted: 20 October 1999 / Published: 25 October 1999
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| Download PDF Full-text (22 KB) Abstract: A method to synthesize desmethylclozapine, 3, is reported. The procedure afforded the target compound in 69% yield. A by-product, isolated from the reaction mixture in 11% yield, proved to be the title compound, 4.
p. 333-337
Received: 11 October 1999 / Accepted: 20 October 1999 / Published: 25 November 1999
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| Download PDF Full-text (31 KB) Abstract: N -Substituted amides and lactams are rapidly N -alkylated under solvent-free phase-transfer catalytic conditions using microwaves.
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