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Molecules 1999, 4(10), 264-271; doi:10.3390/41000264

Fluorescent 2,7-Dialkylamino-[1,8]-Naphthyridines: Preparation and Spectroscopic Properties

1,* , 2 and 2
1 BYK-Gulden-Lomberg GmbH, D-78467 Konstanz, Germany 2 Institute for Virology, University of Jena, Winzerlaerstr. 10, D-07745 Jena, Germany
* Author to whom correspondence should be addressed.
Received: 4 June 1999 / Accepted: 10 August 1999 / Published: 6 September 1999
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Substitution of 4-methyl-[1,8]-naphthyridine in 2 and 7 position by alkylamines leads to highly fluorescent compounds. The arrangement of hydrogen donor and acceptor groups of these naphthyridines allows interactions with guanine and guanine cytosine base pairs. The described synthesis offers easy access to these small and stable fluorescent probes.
Keywords: Naphthyridines; Fluorescence; Fluorescent probes Naphthyridines; Fluorescence; Fluorescent probes
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Hoock, C.; Reichert, J.; Schmidtke, M. Fluorescent 2,7-Dialkylamino-[1,8]-Naphthyridines: Preparation and Spectroscopic Properties. Molecules 1999, 4, 264-271.

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