Host–Virus Interactions and Vaccine Development
A special issue of Vaccines (ISSN 2076-393X).
Deadline for manuscript submissions: 31 December 2024 | Viewed by 900
Special Issue Editor
2. Research and Development Center for Nasal Mucosal Vaccine, Shin Nippon Biomedical Laboratories, Ltd., 2438 Miyanoura, Kagoshima 891-1394, Japan
Interests: host restriction factors; retroviruses; APOBEC3; epitopes; CD4-positive T-lymphocyte; vaccine strategies; resistance to infection; immune regulatory genes; autoimmune diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Host genetic factors, exemplified by MHC restriction, strictly regulate immune responses against viruses. However, innate responses are also under genetic control and affect vaccine efficacies. Correlates of protection against viral infections are explored and defined for practical purposes, but they may not reflect mechanisms of protection that operate in vivo. Thus, virus-neutralizing antibodies may not only interfere with viral attachment and entry to host cells but can also facilitate adaptive immune responses through immune complex formation, complement activation, and binding to receptors on antigen-presenting cells. A more profound understanding of genetically regulated defense mechanisms is essential for the more strategic development of antiviral vaccines.
This Special Issue summarizes recent advances in host genetic control of intracellular defense mechanisms, innate and adaptive immune responses, and their interactions in viral infections. We also welcome original research reports closely related to host–virus interactions and vaccine development.
Prof. Dr. Masaaki Miyazawa
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- virus infection
- host genes
- immune regulation
- innate immunity
- immunological memory
- vaccine efficacy
