Immune Response after Respiratory Infection and Vaccination

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Cellular/Molecular Immunology".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 434

Special Issue Editor


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Guest Editor
Department of Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China
Interests: infectious disease epidemiology; evaluation of vaccine efficacy; vaccine development
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The immune response to respiratory tract infections, including influenza and coronaviruses, is complex, underscoring the need to better understand the multifaceted response of the human immune system. Virus strains and variants and their potential for co-circulation, e.g., influenza and coronaviruses, contribute to the complexity of this dynamic environment.

In this Special Issue, we will examine the latest developments in the immune, epidemiological, and clinical characteristics of influenza and coronavirus co-infection. Key topics may include the following:

  1. The temporal dynamics of the immune response to viral co-infections;
  2. The key factors that influence virus clearance;
  3. Factors that contribute to the formation and development of immune memory in response to co-infections;
  4. The examination of influenza and coronavirus vaccines and their protection of the host in the context of co-infection are encouraged, including the key challenges that may hinder the development of vaccines for co-infections.

This Special Issue aims to provide a significant platform for cutting-edge research and insights.

Dr. Dingmei Zhang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • immune response to viral co-infections
  • immune memory in response to co-infections
  • influenza and coronavirus vaccines
  • vaccines for co-infections

Published Papers (1 paper)

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Research

12 pages, 781 KiB  
Article
Have Previous COVID-19 Vaccinations Shaped the Potential Enhancing Infection of Variant Strains?
by Husheng Xiong, Xiang Meng, Yanqin Song, Jiayi Zhong, Shuang Liu, Xun Zhu, Xin Ye, Yonghui Zhong and Dingmei Zhang
Vaccines 2024, 12(6), 567; https://doi.org/10.3390/vaccines12060567 - 22 May 2024
Viewed by 248
Abstract
Objective: This study aimed to investigate the infection status of Omicron in the population and the association between COVID-19 vaccination and infection with Omicron. Methods: We conducted a cross-sectional study to openly recruit participants for a survey of SARS-CoV-2 infection by convenience sampling [...] Read more.
Objective: This study aimed to investigate the infection status of Omicron in the population and the association between COVID-19 vaccination and infection with Omicron. Methods: We conducted a cross-sectional study to openly recruit participants for a survey of SARS-CoV-2 infection by convenience sampling from 1 January to 15 January 2023 after a COVID-19 pandemic swept across China. Additionally, the binary logistic regression model was adopted to evaluate the association between COVID-19 vaccination and the infection outcomes or symptom severity, respectively. Meanwhile, the relations between the vaccination and duration of the symptoms were estimated via ordinal logistic analysis. Results: Of the 2007 participants, the prevalence of infection with Omicron was 82.9%. Compared with unvaccinated individuals, inactivated COVID-19 vaccination could increase the risk of Omicron infection (OR = 1.942, 95% CI: 1.093–3.448), and the receipt of at least one dose of non-inactivated COVID-19 vaccines was a protective factor against infection (OR = 0.428, 95% CI: 0.226–0.812). By contrast, no relations were observed in COVID-19 vaccination with the symptoms of infection and duration of symptoms (p > 0.05). Conclusions: This cross-sectional study concluded that inactivated COVID-19 vaccination might increase the risk of Omicron infection, which should be a concern during COVID-19 vaccination and the treatment of variant infections in the future, and the receipt of at least one dose of non-inactivated COVID-19 vaccine was a protective factor against infection. Full article
(This article belongs to the Special Issue Immune Response after Respiratory Infection and Vaccination)
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