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Special Issue "Advanced Sensors for Toxins"

A special issue of Toxins (ISSN 2072-6651).

Deadline for manuscript submissions: 31 March 2018

Special Issue Editors

Guest Editor
Prof. Dr. Jean-Louis Marty

BAE (Biosensor Analysis Environment), Université de Perpignan Via Domitia, 52 avenue Paul Alduy, 66860 Perpignan CEDEX France
Website | E-Mail
Phone: + 33 (0) 4 68 66 22 54
Fax: + 33 (0) 4 68 66 22 23
Interests: electrochemical and optical biosensors; environment and agro food fields; pollutants and toxins; screen printed electrodes; aptamers
Guest Editor
Dr. Gaelle Catanante

BAE-LBBM-USR CNRS 3579, Université de Perpignan Via Domitia , 52 avenue paul allude, 66860 Perpignan cedex, France
E-Mail
Guest Editor
Dr. Akhtar Hayat

Interdisciplinary Research Centre in Biomedical Materials (IRCBM) COMSATS Institute of Information Technology, 54000 Lahore, Pakistan
Website | E-Mail
Interests: nanomaterials; aptamer/aptasensor; immuno-assay/sensors; enzyme-assay/sensors; electrochemical/colorimetric/fluorescence sensors/biosensors; medical/food/environmental applications

Special Issue Information

Dear Colleagues,

Biological toxins are produced by living organisms and are generally toxic at low concentrations. We are aware of the omnipresence and variability of these toxins in many matrices. These toxins are not often monitored, but have the potential to enter the environment, resulting adverse ecological and human health effects. Political, industrial and academic leaders are aware of the urgent need for robust, rapid, and low-cost methods to detect low concentrations of these toxins in various matrices. Many sensors and biosensors have been described in the literature for the detection of numerous toxins. The goal is the development of new sensors “advanced biosensors”. Our objective is to target these advances sensors and biosensors with respect to the mechanism of molecular recognition, material design, and characterization, sensing procedure. We note that, in spite of the promising approaches demonstrated thus far, much work still needs to be done before they become a viable alternative to conventional methods.

Prof. Dr. Jean Louis Marty
Dr. Gaelle Catanante
Dr. Akhtar Hayat
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Sensor
  • Biosensor
  • Biological Toxins
  • Small molecules
  • Electrochemical
  • Optical
  • Gravimetric
  • Portable

Published Papers (1 paper)

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Open AccessPerspective Molecular Modeling and Simulation Tools in the Development of Peptide-Based Biosensors for Mycotoxin Detection: Example of Ochratoxin
Toxins 2017, 9(12), 395; doi:10.3390/toxins9120395
Received: 7 November 2017 / Revised: 28 November 2017 / Accepted: 3 December 2017 / Published: 6 December 2017
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Abstract
Mycotoxin contamination of food and feed is now ubiquitous. Exposures to mycotoxin via contact or ingestion can potentially induce adverse health outcomes. Affordable mycotoxin-monitoring systems are highly desired but are limited by (a) the reliance on technically challenging and costly molecular recognition by
[...] Read more.
Mycotoxin contamination of food and feed is now ubiquitous. Exposures to mycotoxin via contact or ingestion can potentially induce adverse health outcomes. Affordable mycotoxin-monitoring systems are highly desired but are limited by (a) the reliance on technically challenging and costly molecular recognition by immuno-capture technologies; and (b) the lack of predictive tools for directing the optimization of alternative molecular recognition modalities. Our group has been exploring the development of ochratoxin detection and monitoring systems using the peptide NFO4 as the molecular recognition receptor in fluorescence, electrochemical and multimodal biosensors. Using ochratoxin as the model mycotoxin, we share our perspective on addressing the technical challenges involved in biosensor fabrication, namely: (a) peptide receptor design; and (b) performance evaluation. Subsequently, the scope and utility of molecular modeling and simulation (MMS) approaches to address the above challenges are described. Informed and enabled by phage display, the subsequent application of MMS approaches can rationally guide subsequent biomolecular engineering of peptide receptors, including bioconjugation and bioimmobilization approaches to be used in the fabrication of peptide biosensors. MMS approaches thus have the potential to reduce biosensor development cost, extend product life cycle, and facilitate multi-analyte detection of mycotoxins, each of which positively contributes to the overall affordability of mycotoxin biosensor monitoring systems. Full article
(This article belongs to the Special Issue Advanced Sensors for Toxins)
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