Special Issue "Bacterial Protein Toxins"

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A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Bacterial Toxins".

Deadline for manuscript submissions: closed (30 November 2009)

Special Issue Editors

Guest Editor
Dr. Yasuhiko Horiguchi
Research Institute for Microbial Diseases, Osaka University, Yamada-oka 3-1, Suita, Osaka 565-0871, Japan
Website: http://www.biken.osaka-u.ac.jp/act/act_horiguchi_e.php
E-Mail: horiguti@biken.osaka-u.ac.jp
Phone: +81 6 6879 8284
Fax: + 81 6 6879 8283
Interests: structure and domain organization of proteins; cell-to -cell or intracellular signaling; receptors for toxins; membrane-damaging toxins

Guest Editor
Dr. Yukako Fujinaga
Laboratory for Infection Cell Biology, International Research Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Yamada-oka 3-1, Suita, Osaka 565-0871, Japan
Website: http://www.biken.osaka-u.ac.jp/act/act_fujinaga_e.php
E-Mail: yukafuji@biken.osaka-u.ac.jp
Phone: +81 6 6879 4250
Fax: +81 6 6879 4252
Interests: bacterial protein toxins; enterotoxins; mechanism of toxicity; interaction of toxins with epithelial cell barriers

Special Issue Information

Dear Colleagues,

Bacterial protein toxins play an important role in infectious diseases. Several are highly potent human poisons, such as botulinum, tetanus, Shiga, and diphtheria toxins. These toxins are multi-functional proteins that are self-programmed to reach their target organs and/or enter cells. Another set of toxins is called effector, which is directly delivered into the cell by type III/IV mechanisms. To exert their potency, many of them interact specifically with key components of the cell. Thus, these toxins are not only responsible for disease, but also provide a powerful set of tools with which to elucidate complicated machinery of the cell system. In addition, some toxins can be used medicinally to treat human diseases, such as Botox (botulinum toxin) in recent years. This issue of Toxins will deal with major achievements and recent exciting discoveries in protein toxins and effectors produced by bacteria, including three-dimensional structures, structure-activity relationships, toxin receptors, toxin substrates, toxin trafficking, and clinical applications.

Yukako Fujinaga, Ph. D.
Yasuhiko Horiguchi, Ph. D.
Guest Editors

Keywords

  • exotoxin
  • virulence factor
  • enzyme
  • pore formation
  • effector protein

Published Papers (8 papers)

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Displaying article 1-8
p. 665-682
by ,  and
Toxins 2010, 2(4), 665-682; doi:10.3390/toxins2040665
Received: 7 February 2010; in revised form: 30 March 2010 / Accepted: 9 April 2010 / Published: 13 April 2010
Show/Hide Abstract | Cited by 9 | PDF Full-text (375 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Bacterial Protein Toxins)
p. 283-296
by ,  and
Toxins 2010, 2(2), 283-296; doi:10.3390/toxins2020282
Received: 4 February 2010; in revised form: 20 February 2010 / Accepted: 20 February 2010 / Published: 23 February 2010
Show/Hide Abstract | Cited by 4 | PDF Full-text (226 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Bacterial Protein Toxins)
p. 215-228
by  and
Toxins 2010, 2(2), 215-228; doi:10.3390/toxins2020215
Received: 1 December 2009; in revised form: 13 January 2010 / Accepted: 27 January 2010 / Published: 28 January 2010
Show/Hide Abstract | Cited by 9 | PDF Full-text (252 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Bacterial Protein Toxins)
p. 205-214
by  and
Toxins 2010, 2(2), 205-214; doi:10.3390/toxins2020205
Received: 24 November 2009; in revised form: 19 January 2010 / Accepted: 27 January 2010 / Published: 28 January 2010
Show/Hide Abstract | Cited by 3 | PDF Full-text (991 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Bacterial Protein Toxins)
p. 116-127
by  and
Toxins 2010, 2(1), 116-127; doi:10.3390/toxins2010116
Received: 14 December 2009; in revised form: 15 January 2010 / Accepted: 20 January 2010 / Published: 21 January 2010
Show/Hide Abstract | Cited by 5 | PDF Full-text (394 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Bacterial Protein Toxins)
p. 69-92
by  and
Toxins 2010, 2(1), 69-92; doi:10.3390/toxins2010069
Received: 3 December 2009; in revised form: 31 December 2009 / Accepted: 14 January 2010 / Published: 15 January 2010
Show/Hide Abstract | Cited by 7 | PDF Full-text (1833 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Bacterial Protein Toxins)
p. 208-228
by , , ,  and
Toxins 2009, 1(2), 208-228; doi:10.3390/toxins1020208
Received: 27 November 2009; in revised form: 16 December 2009 / Accepted: 21 December 2009 / Published: 23 December 2009
Show/Hide Abstract | Cited by 6 | PDF Full-text (2256 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Bacterial Protein Toxins)
p. 123-133
by
Toxins 2009, 1(2), 123-133; doi:10.3390/toxins1020123
Received: 2 November 2009; in revised form: 13 November 2009 / Accepted: 26 November 2009 / Published: 1 December 2009
Show/Hide Abstract | Cited by 2 | PDF Full-text (491 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Bacterial Protein Toxins)
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Last update: 5 March 2014

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