Special Issue "Bacterial Protein Toxins"
A special issue of Toxins (ISSN 2072-6651).
Deadline for manuscript submissions: closed (30 November 2009)
Dr. Yasuhiko Horiguchi
Research Institute for Microbial Diseases, Osaka University, Yamada-oka 3-1, Suita, Osaka 565-0871, Japan
Phone: +81 6 6879 8284
Fax: + 81 6 6879 8283
Interests: structure and domain organization of proteins; cell-to -cell or intracellular signaling; receptors for toxins; membrane-damaging toxins
Dr. Yukako Fujinaga
Laboratory for Infection Cell Biology, International Research Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Yamada-oka 3-1, Suita, Osaka 565-0871, Japan
Phone: +81 6 6879 4250
Fax: +81 6 6879 4252
Interests: bacterial protein toxins; enterotoxins; mechanism of toxicity; interaction of toxins with epithelial cell barriers
Bacterial protein toxins play an important role in infectious diseases. Several are highly potent human poisons, such as botulinum, tetanus, Shiga, and diphtheria toxins. These toxins are multi-functional proteins that are self-programmed to reach their target organs and/or enter cells. Another set of toxins is called effector, which is directly delivered into the cell by type III/IV mechanisms. To exert their potency, many of them interact specifically with key components of the cell. Thus, these toxins are not only responsible for disease, but also provide a powerful set of tools with which to elucidate complicated machinery of the cell system. In addition, some toxins can be used medicinally to treat human diseases, such as Botox (botulinum toxin) in recent years. This issue of Toxins will deal with major achievements and recent exciting discoveries in protein toxins and effectors produced by bacteria, including three-dimensional structures, structure-activity relationships, toxin receptors, toxin substrates, toxin trafficking, and clinical applications.
Yukako Fujinaga, Ph. D.
Yasuhiko Horiguchi, Ph. D.
All papers should be submitted to email@example.com with copy to the guest editor. To be published continuously until the deadline and papers will be listed together at the special websites.
Submitted papers should not have been previously published nor be currently under consideration for publication elsewhere. All papers are refereed through a peer review process. A guide for authors, sample copies and other relevant information for submitting papers are available on the Instructions for Authors page. Toxins is an international peer-reviewed monthly journal published by MDPI.
Article Processing Charges (APC) for publication in this open access journal are waived for well-prepared manuscripts submitted by 30 June 2010. English correction or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those paper accepted for publication, that require extensive additional formatting and/or English corrections.
- virulence factor
- pore formation
- effector protein
Toxins 2009, 1(2), 123-133; doi:10.3390/toxins1020123
Received: 2 November 2009; in revised form: 13 November 2009 / Accepted: 26 November 2009 / Published: 1 December 2009| Download PDF Full-text (491 KB) | Download XML Full-text
Toxins 2009, 1(2), 208-228; doi:10.3390/toxins1020208
Received: 27 November 2009; in revised form: 16 December 2009 / Accepted: 21 December 2009 / Published: 23 December 2009| Download PDF Full-text (2256 KB) | Download XML Full-text
Article: The Versatility of the Helicobacter pylori Vacuolating Cytotoxin VacA in Signal Transduction and Molecular Crosstalk
Toxins 2010, 2(1), 69-92; doi:10.3390/toxins2010069
Received: 3 December 2009; in revised form: 31 December 2009 / Accepted: 14 January 2010 / Published: 15 January 2010| Download PDF Full-text (1833 KB) | Download XML Full-text
Toxins 2010, 2(1), 116-127; doi:10.3390/toxins2010116
Received: 14 December 2009; in revised form: 15 January 2010 / Accepted: 20 January 2010 / Published: 21 January 2010| Download PDF Full-text (394 KB) | Download XML Full-text
Toxins 2010, 2(2), 215-228; doi:10.3390/toxins2020215
Received: 1 December 2009; in revised form: 13 January 2010 / Accepted: 27 January 2010 / Published: 28 January 2010| Download PDF Full-text (252 KB) | Download XML Full-text
Toxins 2010, 2(2), 205-214; doi:10.3390/toxins2020205
Received: 24 November 2009; in revised form: 19 January 2010 / Accepted: 27 January 2010 / Published: 28 January 2010| Download PDF Full-text (991 KB) | Download XML Full-text
Article: Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1): Toxin Biology, in Vivo Applications and Therapeutic Potential
Toxins 2010, 2(2), 283-296; doi:10.3390/toxins2020282
Received: 4 February 2010; in revised form: 20 February 2010 / Accepted: 20 February 2010 / Published: 23 February 2010| Download PDF Full-text (226 KB) | Download XML Full-text
Review: Clostridial Neurotoxins: Mechanism of SNARE Cleavage and Outlook on Potential Substrate Specificity Reengineering
Toxins 2010, 2(4), 665-682; doi:10.3390/toxins2040665
Received: 7 February 2010; in revised form: 30 March 2010 / Accepted: 9 April 2010 / Published: 13 April 2010| Download PDF Full-text (375 KB) | Download XML Full-text
Last update: 12 January 2011