Special Issue "Molecular Adhesion Codes in Geometric Regulation of Bilaterian Morphogenesis"


A special issue of Symmetry (ISSN 2073-8994).

Deadline for manuscript submissions: closed (30 June 2014)

Special Issue Editor

Guest Editor
Dr. David A. Becker

Department of Chemistry and Biochemistry, Florida International University, Miami, FL 33199, USA
Website: http://chemistry.fiu.edu/faculty/david-becker/
Fax: +1 305 348 3772
Interests: azulenyl nitrones; spin trapping; neuroprotection; free radicals; morphogenesis; bilateral symmetry; cadherins; zygo-dodecahedral brain model; geometrical music theory

Special Issue Information

Dear Colleagues,

Leonardo Da Vinci’s famous “Vitruvian Man” is a work that, in many, evokes a profound appreciation for the importance of symmetry and geometry in the underlying morphogenetic phenomena that intrinsically govern the assemblage of trillions of cells into the precise configuration that characterizes the human body plan. Can science unravel the elegant forces that so adroitly shape us? Great strides in this direction for various bilaterians have emerged (e.g., Shh, homeobox codes, BMP, chordin, WNT), yet the picture is far from complete.
The last decade has seen a number of studies highlighting the role of sets of cell adhesion molecules such as cadherins in the patterning of structures in the developing chicken spinal cord, the murine basal ganglia, and the legs of the insect gryllus bimaculatus. Recent work has put forth the notion that the overall morphology of the human brain is that of an icosahedrally-derived zygo-dodecahedron and that known heterophilic binding proclivities of certain type II cadherins may figure prominently in the construction of such a zygo-dodecahedral entity. This special issue of Symmetry welcomes contributions that document forays, be they experimental or theoretical, into molecular adhesion networks as geometric underpinnings in the developmental biology that gives rise to the bodies and/or body parts of either humans or other animals within the vast bilaterian subkingdom.

Prof. Dr. David A. Becker
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Symmetry is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 800 CHF (Swiss Francs).


  • morphogenesis
  • developmental biology
  • cell adhesion molecules
  • adhesion networks
  • biogeometry
  • bilaterians

Published Papers (1 paper)

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p. 704-721
Symmetry 2014, 6(3), 704-721; doi:10.3390/sym6030704
Received: 29 June 2014 / Revised: 29 July 2014 / Accepted: 4 August 2014 / Published: 14 August 2014
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Last update: 6 January 2014

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