Recent Advances in Improving or Preserving Therapeutic Potential of Extracellular Vesicles as Regenerative Medicines
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Biologics and Biosimilars".
Deadline for manuscript submissions: closed (10 August 2022) | Viewed by 2642
Special Issue Editors
Interests: hybrid nanoparticles as theranostic nanomedicine; polymeric conjugates for cancer immunotherapy; antibody conjugates for regulation of immune checkpoints; injectable hydrogels for tissue engineering; siRNA delivery systems; therapeutic exosomes
Special Issues, Collections and Topics in MDPI journals
Interests: polymeric nanomedicine; exosome; drug delivery system; therapeutic ultrasound
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs) are intercellular communication tools that carry effector biomolecules inside to mediate normal physiological processes and disease pathogenesis. In particular, regenerative and immunomodulatory EVs have been highly regarded as innate bio-therapeutics to treat a variety of diseases during the past decade. Although stem cells are the main source of producing these EVs, related research has expanded to utilize immune cells and specific organ-originated cells.
We are seeking recent efforts in the field of regenerative medicine for enhancing the therapeutic efficacy, efficiency, and stability of EVs to foster their clinical translation using three specific approaches: (1) preconditioning to improve EV bioactivity by applying chemical or physical stimuli, (2) surface modification for transporting EVs properly to the lesion by introduction of targeting components on them, and (3) development of formulations to preserve the structural integrity and therapeutic components of EVs.
Prof. Dr. Jae Hyung Park
Dr. Seunglee Kwon
Guest Editors
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Keywords
- extracellular vesicle
- exosome
- regenerative medicine
- therapeutic application
- preconditioning
- surface modification
- targeting
- formulation
- stability
