Mechanistic In Vitro and In Silico Modeling of Oral Drug Absorption
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".
Deadline for manuscript submissions: closed (31 July 2020) | Viewed by 44666
Special Issue Editor
Interests: oral absorption; gastrointestinal physiology; drug property; in vitro model; mechanistic model; modeling and simulation literacy
Special Issue Information
Dear Collegaues,
Mechanistic in vitro and in silico modeling of oral drug absorption is anticipated to enable accurate in vivo prediction. To achieve this goal, a better understanding of gastrointestinal physiology, drug properties, and molecular-level mechanisms is critically important.The aim of this Special Issue is to highlight current progress in this field. The scope of this issue includes in vitro models, mathematical mechanistic models, gastrointestinal physiology, drug properties, and related areas in oral drug absorption. In addition, modeling and simulation (M&S) literacy is the key to progress. Easy case-by-case parameter fitting underlies the sound development of sciences, as Ptolemy’s model did for astronomy over 1300 years. Therefore, articles related to M&S literacy are also welcome (e.g., identifiability analysis).
Prof. Kiyohiko Sugano
Guest Editor
Manuscript Submission Information
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Keywords
- oral absorption
- gastrointestinal physiology
- drug property
- in vitro model
- mechanistic model
- modeling and simulation literacy