Recent Advances in Pulmonary Drug Delivery Systems

Dear Colleagues,

In recent years, pulmonary drug delivery systems have become a method of drug delivery that has attracted much attention. PDDSs refer to a special dosage form that is administered with a special device, such that a drug acts on the lungs and exerts local or systemic effects through the deep part of the respiratory tract. Pulmonary drug delivery systems have the advantages of being non-invasive, a quick onset, fewer local metabolic enzymes, and localized drug delivery, and are widely used in the treatment of respiratory diseases.

Despite several decades of research, the pulmonary delivery of biologics and high-dose active pharmaceutical ingredients, i.e., antibiotic, antibacterial, and antiviral drugs, is still challenging. There is still a significant gap between scientific research and clinical translation in enhancing lung deposition and bioavailability.

This Special Issue aims to collect the latest advances and state-of-the-art developments in the field of pulmonary drug delivery systems, including (but are not limited to) advanced drug delivery platforms for the treatment of respiratory diseases, in vitro/in silico/in vivo studies on the pulmonary drug delivery process and pulmonary deposition, the design of novel inhaler devices, studies relevant to potential lung toxicity and adverse effects of the excipients, and advanced delivery approaches for biopharmaceuticals. Notably, pulmonary drug delivery systems with high translational potential will be particularly preferred. Original research and review papers that reflect this topic’s status quo are warmly welcomed.

Prof. Dr. Chuanbin Wu
Dr. Xuejuan Zhang
Dr. Sha Li
Guest Editors

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• pulmonary drug delivery systems
• dry powder inhalation
• inhalation drug delivery
• inhalation formulation and process development
• design of novel inhaler devices
• inhalation excipients
• delivery processes of pulmonary drugs
• inhalation nanoparticles
• aerosol inhalation
• pressurized metered-dose inhalation