Special Issue "Mitochondrial Target-Based Drug Discovery"
A special issue of Pharmaceuticals (ISSN 1424-8247).
Deadline for manuscript submissions: closed (15 March 2015)
Prof. Dr. Philip Hogg (Website)
Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW 2052, Australia
Fax: +61 2 9385 1510
Interests: allosteric disulfide bonds; small molecule mitochondrial pharmaceuticals; cancer
Dr. Pierre Dilda (Website)
Prince of Wales Clinical School, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, 2052, Australia
Interests: drug discovery; cancer drug development and pharmacology; drug resistance; medicinal chemistry; arsenical-based drugs
Compared to healthy cells, cancerous ones catabolize nutrients differently. Mitochondria play a central role in this altered metabolism. Mitochondria coordinate the catabolism of glucose and glutamine across the cancer cell. Disrupting this metabolism may potentially treat the disease. This special issue focuses on small molecules that inhibit the cancer cell mitochondrial metabolism, which are in pre-clinical or clinical development.
Prof. Dr. Philip Hogg
Dr. Pierre Dilda
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed Open Access quarterly journal published by MDPI.
- outer-mitochondrial membrane
- inner-mitochondrial membrane
- mitochondrial matrix