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Impact of DHA/EPA and Other Nutrients on Development: From Perinatal...
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Impact of DHA/EPA and Other Nutrients on Development: From Perinatal to Menopause

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition in Women".

Deadline for manuscript submissions: closed (15 February 2023) | Viewed by 8829

Special Issue Editors

Dr. Paolo Brambilla

E-Mail Website
Guest Editor
Department of Medical-Surgical Physiopathology and Transplantation, University of Milan, 20122 Milan, Italy
Interests: mental health; mental diseases; affective disorders; personalized medicine; neuroimaging; neuropsychology
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Carlo Agostoni

E-Mail Website
Co-Guest Editor
Department of Clinical Sciences and Community Health (DISCCO), University of Milan, 20122 Milan, Italy
Interests: n-3 polyunsaturated fatty acids; nutrition; lipid metabolism; metabolic diseases; EPA; DHA; neurodevelopment
Special Issues, Collections and Topics in MDPI journals
Dr. Alessandra Mazzocchi

E-Mail Website
Co-Guest Editor
Department of Clinical Sciences and Community Health, University of Milano, 20122 Milano, Italy
Interests: human nutrition; metabolism; body composition; nutritional status

Special Issue Information

Dear Colleagues,

We are pleased to invite contributions of original research or reviews to extend our understanding of the role of nutrients, physical exercise and lifestyle for the treatment of gender-related major mental illnesses.

Anxiety, depression and psychoses are major mental disorders that currently affect hundreds of millions of people worldwide and affect women across their entire lifespan, particularly in relation to major depression and general anxiety disorder. In addition to the various available psychotropic drugs, current potential adjunctive treatment for these disabling illnesses includes novel therapeutic strategies, such as nutritional supplements, physical exercise and lifestyle adjustment.

This Special Issue will highlight recent research on the role of specific nutrients, such as the n-3 long-chain polyunsaturated fatty acids, as well as physical exercise and lifestyle, as coadjuvant therapies for women experiencing episodes of anxiety, depressive or psychotic episodes in their life span, in particular during “windows of vulnerability”, i.e., when exposed to intense hormone fluctuations, such as the peripartum period or the menopause transition.

Evidence concerning the health benefits of DHA and EPA and multisystemic approaches and their preventive effect on mental disorders, and all the related disabling symptoms, is growing.

We invite you to submit your research covering these important topics. Submissions of original papers, reviews or meta-analyses on humans are particularly welcome.

Dr. Paolo Brambilla
Guest Editor

Prof. Dr. Carlo Agostoni
Dr. Alessandra Mazzocchi
Co-Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • DHA
  • EPA
  • n-3 LCPUFAs
  • Diet
  • Physical exercise
  • Depression
  • Perinatal depression
  • Menopause

Published Papers (1 paper)

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Review

39 pages, 2179 KiB  
Review
The Problem of Malnutrition Associated with Major Depressive Disorder from a Sex-Gender Perspective
by Cielo García-Montero, Miguel A. Ortega, Miguel Angel Alvarez-Mon, Oscar Fraile-Martinez, Adoración Romero-Bazán, Guillermo Lahera, José Manuel Montes-Rodríguez, Rosa M. Molina-Ruiz, Fernando Mora, Roberto Rodriguez-Jimenez, Javier Quintero and Melchor Álvarez-Mon
Nutrients 2022, 14(5), 1107; https://doi.org/10.3390/nu14051107 - 6 Mar 2022
Cited by 11 | Viewed by 8201
Abstract
Major depressive disorder (MDD) is an incapacitating condition characterized by loss of interest, anhedonia and low mood, which affects almost 4% of people worldwide. With rising prevalence, it is considered a public health issue that affects economic productivity and heavily increases health costs [...] Read more.
Major depressive disorder (MDD) is an incapacitating condition characterized by loss of interest, anhedonia and low mood, which affects almost 4% of people worldwide. With rising prevalence, it is considered a public health issue that affects economic productivity and heavily increases health costs alone or as a comorbidity for other pandemic non-communicable diseases (such as obesity, cardiovascular disease, diabetes, inflammatory bowel diseases, etc.). What is even more noteworthy is the double number of women suffering from MDD compared to men. In fact, this sex-related ratio has been contemplated since men and women have different sexual hormone oscillations, where women meet significant changes depending on the age range and moment of life (menstruation, premenstruation, pregnancy, postpartum, menopause…), which seem to be associated with susceptibility to depressive symptoms. For instance, a decreased estrogen level promotes decreased activation of serotonin transporters. Nevertheless, sexual hormones are not the only triggers that alter neurotransmission of monoamines and other neuropeptides. Actually, different dietary habits and/or nutritional requirements for specific moments of life severely affect MDD pathophysiology in women. In this context, the present review aims to descriptively collect information regarding the role of malnutrition in MDD onset and course, focusing on female patient and especially macro- and micronutrient deficiencies (amino acids, ω3 polyunsaturated fatty acids (ω3 PUFAs), folate, vitamin B12, vitamin D, minerals…), besides providing evidence for future nutritional intervention programs with a sex-gender perspective that hopefully improves mental health and quality of life in women. Full article
(This article belongs to the Special Issue Impact of DHA/EPA and Other Nutrients on Development: From Perinatal to Menopause)
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