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Nutrients
Special Issues
Relationships between Dietary Factors and Inflammatory Skin Diseases
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Relationships between Dietary Factors and Inflammatory Skin Diseases

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: 5 December 2024 | Viewed by 5627

Special Issue Editor

Dr. Anja Saalbach

E-Mail Website
Guest Editor
Department of Dermatology, Venereology and Allergology, University of Leipzig Medical Center, 04103 Leipzig, Germany
Interests: regulation of inflammation and wound healing in obesity; role of free fatty acids in inflammation; interplay of dermal cells in inflammation and wound healing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Chronic inflammatory skin diseases, such as psoriasis, acne, atopic dermatitis or contact dermatitis, strongly decrease one’s health-related quality of life. Despite the existence of efficient treatment options, these are most often lifelong chronic diseases. Several studies have established that nutritional and dietary factors play an important role in maintaining normal skin integrity and that they may play a pathogenic, preventive and/or therapeutic role in a number of skin-related diseases. Researchers have studied the role of dietary factors in skin aging, acne, inflammation, and several chronic immune-mediated diseases, such as atopic dermatitis, psoriasis, diabetes, obesity, and wounds.

Our goal is to explore all the theoretical and practical knowledge that is related to dietary factors and inflammatory skin diseases. You are welcome to submit original research articles or reviews of the scientific literature on the role of diet and/or specific nutrients in the prevention and treatment of skin diseases related to “Relationships Between Dietary Factors and Inflammatory Skin Diseases”

Dr. Anja Saalbach
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dietary
  • nutrition
  • food
  • skin
  • skin disease

Published Papers (2 papers)

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Research

13 pages, 259 KiB  
Article
Nurturing Infants to Prevent Atopic Dermatitis and Food Allergies: A Longitudinal Study
by Emilia Vassilopoulou, Dimitrios Rallis, Gregorio Paolo Milani, Carlo Agostoni, Gavriela Feketea, Maria Lithoxopoulou, Evangelia Stefanaki, Fani Ladomenou, Nikolaos Douladiris, Caoimhe Cronin, Codruta Alina Popescu, Raluca Maria Pop, Ioana Corina Bocsan and Sophia Tsabouri
Nutrients 2024, 16(1), 21; https://doi.org/10.3390/nu16010021 - 20 Dec 2023
Viewed by 1183
Abstract
Background: Atopic dermatitis (AD) at a young age often precedes the development of food allergies. Although AD affects millions of infants worldwide, prenatal and postnatal risk factors, and their association with the development of food allergies later on, are not fully elucidated. This [...] Read more.
Background: Atopic dermatitis (AD) at a young age often precedes the development of food allergies. Although AD affects millions of infants worldwide, prenatal and postnatal risk factors, and their association with the development of food allergies later on, are not fully elucidated. This study seeks to investigate AD epidemiology in infancy and its risk factors, examining early-life factors (both prenatal and postnatal) that could contribute to the later development of food allergies. Methods: Between January 2019 and December 2019, 501 infants were included in this prospective cohort study. Longitudinal data collection was performed through maternal interviews, the first one conducted within three days after the delivery and the second within 24 to 36 months after the delivery, encompassing variables such as demographics, family history of atopy, maternal smoking, antibiotic use during pregnancy, the mode of delivery, breastfeeding history, food practices, and greenness exposure within 3 days from delivery, while they were still in the hospital. Results: Maternal smoking during pregnancy (p = 0.001) and an older sibling atopy history (p = 0.03) was significantly linked to AD incidence. Cesarean section delivery (p = 0.04) was associated with a higher risk of food allergies in infants with AD. Having a garden at home correlated with a higher likelihood of AD (p = 0.01), and food elimination without medical guidance (p = 0.02) due to AD correlated with an elevated risk of food allergies. Conclusions: Encouraging timely allergenic food introduction while promoting dietary diversity, rich in plant-based foods, maternal smoking cessation, and professional dietary guidance may help minimize AD and food allergy risk. Future studies should address the role of greenness in the development of AD and food allergies. Full article
(This article belongs to the Special Issue Relationships between Dietary Factors and Inflammatory Skin Diseases)
15 pages, 1246 KiB  
Article
Modulation of Dietary Fatty Acids in an Open-Label Study Improves Psoriasis and Dampens the Inflammatory Activation Status
by Anja Saalbach, Anna-Theresa Seitz, Johannes Kohlmann, Lena Kalweit, Lisa Vogt, Lars Selig, Kathrin M. Engel and Jan C. Simon
Nutrients 2023, 15(7), 1698; https://doi.org/10.3390/nu15071698 - 30 Mar 2023
Viewed by 3958
Abstract
Obesity and high abdominal fat mass are risk factors for developing the chronic inflammatory skin disease psoriasis. They are associated with increased incidence, prevalence and severity of the disease. A positive effect of weight loss on psoriasis activity has been shown in several [...] Read more.
Obesity and high abdominal fat mass are risk factors for developing the chronic inflammatory skin disease psoriasis. They are associated with increased incidence, prevalence and severity of the disease. A positive effect of weight loss on psoriasis activity has been shown in several studies. Obesity-related factors such as the dysregulation of glucose and lipid metabolism, the activation of adipose tissue and resultant persistent low-grade inflammation have been discussed as links of obesity and inflammatory diseases. Recently, we demonstrated a critical role of free fatty acids (FFAs) in obesity-mediated exacerbation of psoriatic skin inflammation in both mice and humans. In the present study, we translated these findings into a therapeutic intervention. An open-label study focusing on the dietary reduction of FFAs was conducted in patients with mild-to-moderate plaque psoriasis, and disease severity and serum markers of inflammation were analyzed. Here, we show that such a dietary intervention improves psoriatic disease activity independently of weight loss. Diet-related metabolic changes, such as a reduction in saturated free fatty acids (SFAs), may thus be more important than weight loss itself. Moreover, dietary intervention inhibited the overall pro-inflammatory activation status in patients, as shown by analysis of serum inflammatory parameters using the Olink platform. From our pilot study, we conclude that dietary intervention focusing on SFA reduction has the capacity to reduce disease activity and general inflammatory status in psoriasis patients. Full article
(This article belongs to the Special Issue Relationships between Dietary Factors and Inflammatory Skin Diseases)
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