Synthesis of α-Aminophosphonic and α-Aminophosphinic Acids and Derivatives
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: 30 June 2024 | Viewed by 170
Special Issue Editors
Interests: synthesis of α-aminophosphonic and α-aminophosphinic acids
Interests: synthetic methodologies; sustainable chemistry; medicinal chemistry; peptidomimetics; phosphonates
Interests: stereoselective synthesis; medicinal chemistry; synthetic methodologies; organophosphorous compounds; unnatural aminoacids
Special Issue Information
Dear Colleagues,
α-Aminophosphonic acids, α-aminophosphinic acids and their derivatives represent a crucial class of compounds with significant importance in both synthetic and medicinal fields. Recent years have witnessed a substantial emphasis on their synthesis, highlighting their fundamental role in various physiologic and pathologic processes, primarily functioning as inhibitors of proteolytic enzymes, where molecular stereochemistry is proven to be of critical importance.
This Special Issue is dedicated to providing a comprehensive overview of the latest developments in the field of α-aminophosphonic and α-aminophosphinic acids. It is organized around three primary themes: (1) the discovery of innovative synthetic methodologies, (2) studies aimed at enhancing the efficiency and generality of existing procedures, (3) the synthesis of novel α-aminophosphonic acids and α-aminophosphinic acids, and (4) the discovery and development of biologically active compounds.
We invite contributions that explore these themes, promoting discussions and knowledge exchanges among researchers at the forefront of the chemistry of these phosphonic and phosphinic analogs of α-amino acids.
By focusing on these areas, this Special Issue aims to consolidate the state-of-the-art in the synthesis of α-aminophosphonic acids, α-aminophosphinic acids, and their derivatives. We anticipate that this collection of research will provide valuable insights and inspire further advances in the field of organophosphorus chemistry.
Prof. Dr. Mario Orodnez
Dr. Ivan Romero-Estudillo
Dr. José Luis Viveros-Ceballos
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- α-aminophosphonic acids
- α-aminophosphinic acids
- stereoselective synthesis
- unnatural aminoacids
- biological activity
