Special Issue "Data Processing in Metabolomics"
A special issue of Metabolites (ISSN 2218-1989).
Deadline for manuscript submissions: closed (31 July 2013)
Dr. Jan Baumbach
Computational Biology Department, Institute for Mathematics and Computer Science, University of Southern Denmark, Campusvej 55, 5230 Odense C, Denmark
Interests: metabolomics; biomarker discovery; disease classification; ion mobility spectrometry
All living cells, throughout all domains of life, control their metabolism in accordance to internal and external conditions. Increasing sensitivity of modern high-throughput spectrometry and chromatography technologies allows us to measure a large fraction of the metabolome of cells, tissues and organs on different scales. The research area of metabolic profiling emerged with a tremendous impact on biomedical research. The hope is to unravel molecular decision processes underlying growth, survival, reproduction and differentiation of cells, tissues, organs and microbial colonies under varying conditions. On a larger scale, we enter the fields of personalized medicine, biomarker discovery & validation as well as therapy optimization. However, the cheaper and faster our technology is, the more data is generated that needs to be analyzed efficiently regarding real-world questions, such as diagnostics, prognosis and in silico modeling of the cell behavior. This special issue will focus on detailing the emerging problems and novel approaches in metabolomics data analysis.
We will consider research papers with special focus on computational methods for analyzing data from typical metabolomics technologies, such as de-noising, smoothing, peak detection, metabolic database design & data integration, disease classification, biomarker identification & validation, disease-sub-typing, data reduction, and metabolic profile alignment. Manuscripts about closely related topics, metabolic network simulation, for instance, are also welcome.
Dr. Jan Baumbach
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed Open Access quarterly journal published by MDPI.
- metabolic profiles
- metabolic patterns
- biomarker detection
- biomarker validation
- personalized medicine
- therapy optimization
- metabolic modeling
- metabolic network simulation
- data integration
- integrated databases