Innovation and Development in NMR-Based Metabolomics for Disease Diagnostics
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Metabolomic Profiling Technology".
Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 2210
Special Issue Editors
Interests: NMR/HR-MAS; metabolomics; bioanalytical chemistry; chemometrics; chem- bio-informatics software development
Special Issue Information
Dear Colleagues,
Metabolomics field embodies a significant share of omics sciences, aiming at the chemical characterization of complex biological matrices through bioanalytical platforms such as nuclear magnetic resonance (NMR). Over the last few decades, both solution and high-resolution magic angle spinning (HR-MAS) NMR technologies have proven to be valuable for the detection as well as quantitation of various chemical entities (i.e., biomarkers) in biofluids, tissues, cells, etc., towards the prognosis and/or diagnosis of several diseases. The simplicity of NMR samples’ preparation, including its non-destructive nature as well as the impeccable reproducibility of NMR data, allow for the detection of unique signatures from pathological conditions, turning the whole NMR profile into a collective biomarker. The successful application of both targeted and untargeted NMR-based metabolomics in biomedicine is the consequence of the continuous advancements in NMR technology/methods/bioinformatics tools, which led to fully automated high-throughput analyses and data interpretation.
This Special Issue will highlight the recent developments in both experimental and computational methods of NMR/HR-MAS technologies in metabolomics combined with their application/validation on real-world samples from pathological conditions. In general, the present Special Issue is designed to cover all NMR/HR-MAS novel strategies (i.e., both experimental and computational methods/tools) for metabolomics studies, aiming at the detection of novel biomarkers for disease diagnosis and/or prognosis. The exploration of any disease metabolic profile via NMR-based approaches will also be considered. Submissions of original research as well as perspective articles are welcome.
Dr. Panteleimon Takis
Dr. Anastassios Troganis
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- NMR/HR-MAS
- metabolomics
- bioinformatics
- cheminformatics
- chemometrics
- biomarkers
- biofluids
- tissues
- diagnostics
