Dietary Compounds and Arsenic Metabolism
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Nutrition and Metabolism".
Deadline for manuscript submissions: closed (16 December 2022) | Viewed by 2119
Special Issue Editors
Interests: untargeted metabolomics and lipidomics; nutrition; exposomics
Special Issues, Collections and Topics in MDPI journals
Interests: toxicity of heavy metals; metabolism of toxic metals; toxicity of chemical substances; oxidative stress
Special Issue Information
Dear Colleagues,
Exposure to arsenic (As) affects people living in many regions of the world, for example, in countries such as Chile, Argentina, Bangladesh, Mexico, Poland, Hungary, Serbia, Romania, Czech Republic, Croatia, Finland, Greece, and Italy. The source of exposure to different chemical forms of As can be both environmental and occupational. Epidemiological studies on individuals exposed to As have shown an increased incidence of cancers and other health problems, such as type 2 diabetes, vascular disease, skin lesions, impaired lung function, and neurological disorders. Inorganic As metabolism involves alternate reactions of methylation and reduction to monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA), and these forms are then excreted by the kidneys. S-adenosyl-methionine synthesized in the one-carbon metabolism (OCM) pathway is an important compound in the methylation process, as the donor of methyl groups. The following dietary compounds are involved in the OCM, mainly as methyl group donors: methionine, choline, betaine, and folic acid. They are also involved as cofactors of the reaction, e.g., vitamin B2, B6, B12, and zinc.
This Special Issue of Metabolites, “Dietary Compounds and Arsenic Metabolism”, will be dedicated to exploring the role of dietary compounds on As metabolism and toxicity. The topics that will be covered by this Special Issue include, but are not limited to, in vivo and in vitro studies on the influence of donors of methyl groups (methionine, choline, betaine, and folic acid), cofactors of reactions (vitamins B2, B6, B12, and zinc), and other dietary compounds on the efficiency of the metabolism process, as well as on the reduction in the severity of the whole spectrum of disorders related to As exposure. In this Special Issue, original research articles and reviews are welcome.
Dr. Lucyna Kozlowska
Dr. Wojciech Wasowicz
Dr. Marek Scieszka
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- inorganic arsenic
- exposure
- health effect
- methylation
- vitamins
- minerals
- bioactive compounds
