Special Issue "Tetrodotoxin"

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A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: closed (15 September 2011)

Special Issue Editor

Guest Editor
Prof. Dr. Peter C. Ruben
Department of Biomedical Physiology & Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC V5A 1S6, Canada
Website: http://www.sfu.ca/bpk/faculty_directory/ruben.html
E-Mail: pruben@sfu.ca
Phone: +1 778 782 9351
Fax: +1 778 782 3040
Interests: voltage-gated ion channels; toxins; evolution

Special Issue Information

Dear Colleagues,

Toxins, and their actions on target molecules, provide insight into predator/prey interactions, co-evolutionary arms races, molecular properties, and structure/function relationships. Toxins also hold promise for therapeutic interventions and serve as a template for rational drug design. Tetrodotoxin is a ubiquitous toxin with highly specific actions. Tetrodotoxin’s ability to block voltage-gated sodium channels has been a fruitful area of research for many years and has led to a number of insights from the molecular level through to the grand scale of evolution. It even has epicurean significance, sometimes with lethal results. Tetrodotoxin has been used as a tool to map the structure and the biophysical properties of voltage-gated sodium channels, and is routinely used to differentiate between sodium channel orthologs.

This special issue of the journal Marine Drugs focuses on tetrodotoxin and seeks to emphasize the importance of the toxin as a research tool, as a potential therapeutic agent, and as a key for understanding animal behavior and natural selection. It is my honor to serve as Guest Editor for this special issue, and to invite scientists to report recent advances on the full spectrum of research questions associated with tetrodotoxin. I eagerly anticipate working with you towards a successful special issue of Marine Drugs dedicated to this important toxin.

Prof. Dr. Peter Ruben
Guest Editor

Keywords

  • voltage-gated sodium channels
  • chemical defense
  • ionic currents
  • puffer fish
  • selectivity filter

Published Papers (18 papers)

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Displaying article 1-18
p. 329-339
by , , , , ,  and
Mar. Drugs 2012, 10(2), 329-339; doi:10.3390/md10020329
Received: 19 December 2011; in revised form: 14 January 2012 / Accepted: 18 January 2012 / Published: 3 February 2012
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(This article belongs to the Special Issue Tetrodotoxin)
p. 281-305
by , , , ,  and
Mar. Drugs 2012, 10(2), 281-305; doi:10.3390/md10020281
Received: 30 December 2011; in revised form: 19 January 2012 / Accepted: 19 January 2012 / Published: 31 January 2012
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(This article belongs to the Special Issue Tetrodotoxin)
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p. 2683-2704
by , ,  and
Mar. Drugs 2011, 9(12), 2683-2704; doi:10.3390/md9122683
Received: 22 September 2011; in revised form: 22 November 2011 / Accepted: 1 December 2011 / Published: 15 December 2011
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(This article belongs to the Special Issue Tetrodotoxin)
p. 2717-2728
by , , , ,  and
Mar. Drugs 2011, 9(12), 2717-2728; doi:10.3390/md9122717
Received: 9 October 2011; in revised form: 18 November 2011 / Accepted: 21 November 2011 / Published: 15 December 2011
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(This article belongs to the Special Issue Tetrodotoxin)
p. 2409-2422
by ,  and
Mar. Drugs 2011, 9(11), 2409-2422; doi:10.3390/md9112409
Received: 20 September 2011; in revised form: 2 November 2011 / Accepted: 10 November 2011 / Published: 21 November 2011
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(This article belongs to the Special Issue Tetrodotoxin)
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p. 2384-2396
by , ,  and
Mar. Drugs 2011, 9(11), 2384-2396; doi:10.3390/md9112384
Received: 24 September 2011; in revised form: 3 November 2011 / Accepted: 4 November 2011 / Published: 14 November 2011
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(This article belongs to the Special Issue Tetrodotoxin)
p. 2283-2290
by
Mar. Drugs 2011, 9(11), 2283-2290; doi:10.3390/md9112283
Received: 19 September 2011; in revised form: 31 October 2011 / Accepted: 1 November 2011 / Published: 8 November 2011
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(This article belongs to the Special Issue Tetrodotoxin)
p. 2291-2303
by ,  and
Mar. Drugs 2011, 9(11), 2291-2303; doi:10.3390/md9112291
Received: 20 September 2011; in revised form: 27 October 2011 / Accepted: 28 October 2011 / Published: 8 November 2011
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(This article belongs to the Special Issue Tetrodotoxin)
p. 2046-2074
by  and
Mar. Drugs 2011, 9(10), 2046-2074; doi:10.3390/md9102046
Received: 9 September 2011; in revised form: 29 September 2011 / Accepted: 11 October 2011 / Published: 20 October 2011
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(This article belongs to the Special Issue Tetrodotoxin)
p. 2153-2161
by , ,  and
Mar. Drugs 2010, 8(7), 2153-2161; doi:10.3390/md8072153
Received: 2 June 2010; in revised form: 24 June 2010 / Accepted: 25 June 2010 / Published: 13 July 2010
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(This article belongs to the Special Issue Tetrodotoxin)
p. 1373-1393
by , ,  and
Mar. Drugs 2010, 8(4), 1373-1393; doi:10.3390/md8041373
Received: 3 February 2010; in revised form: 31 March 2010 / Accepted: 19 April 2010 / Published: 21 April 2010
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(This article belongs to the Special Issue Tetrodotoxin)
p. 1049-1058
by ,  and
Mar. Drugs 2010, 8(4), 1049-1058; doi:10.3390/md8041049
Received: 9 February 2010; in revised form: 23 March 2010 / Accepted: 29 March 2010 / Published: 31 March 2010
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(This article belongs to the Special Issue Tetrodotoxin)
p. 728-740
by , ,  and
Mar. Drugs 2010, 8(3), 728-740; doi:10.3390/md8030728
Received: 15 January 2010; in revised form: 8 February 2010 / Accepted: 18 March 2010 / Published: 19 March 2010
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(This article belongs to the Special Issue Tetrodotoxin)
p. 741-762
by
Mar. Drugs 2010, 8(3), 741-762; doi:10.3390/md8030741
Received: 3 February 2010; in revised form: 11 February 2010 / Accepted: 18 March 2010 / Published: 19 March 2010
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(This article belongs to the Special Issue Tetrodotoxin)
p. 565-576
by , ,  and
Mar. Drugs 2010, 8(3), 565-576; doi:10.3390/md8030565
Received: 3 February 2010; in revised form: 3 March 2010 / Accepted: 5 March 2010 / Published: 10 March 2010
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(This article belongs to the Special Issue Tetrodotoxin)
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p. 577-593
by
Mar. Drugs 2010, 8(3), 577-593; doi:10.3390/md8030577
Received: 24 February 2010; in revised form: 3 March 2010 / Accepted: 8 March 2010 / Published: 10 March 2010
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(This article belongs to the Special Issue Tetrodotoxin)
p. 381-398
by
Mar. Drugs 2010, 8(3), 381-398; doi:10.3390/md8030381
Received: 4 February 2010; in revised form: 24 February 2010 / Accepted: 25 February 2010 / Published: 26 February 2010
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(This article belongs to the Special Issue Tetrodotoxin)
p. 219-234
by  and
Mar. Drugs 2010, 8(2), 219-234; doi:10.3390/md8020219
Received: 23 December 2009; in revised form: 10 January 2010 / Accepted: 28 January 2010 / Published: 1 February 2010
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(This article belongs to the Special Issue Tetrodotoxin)
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Last update: 27 February 2014

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