Special Issue "Marine Antibiotics"

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A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: closed (31 October 2012)

Special Issue Editor

Guest Editor
Prof. Dr. Sergey B. Zotchev
Department of Biotechnology, Norwegian University of Science and Technology, N-7491 Trondheim, Norway
E-Mail: sergey.zotchev@nt.ntnu.no
Phone: +47 73 59 86 79
Fax: +47 73 59 12 83
Interests: streptomycetes; rare actinomycetes; antibiotics; secondary metabolite biosynthesis; engineering of biosynthetic pathways

Special Issue Information

Dear Colleagues,

Since the official discovery of the first antibiotic (penicillin), by Alexander Fleming in 1928, thousands of structurally diverse antibiotics have been reported from a variety of natural sources. Today, antibiotics continue to play the most important role in fighting various types of infections and saving millions of lives every year. However, rapid development of antibiotic resistance by bacterial and fungal pathogens, very limited supply of antiviral and antihelminthic antibiotics, and Big Pharma’s focusing mainly on chronic diseases and cancer represent a formidable challenge for anti-infective therapy of the future.

The absolute majority of currently used antibiotics have been isolated from terrestrial sources, and numerous attempts on terrestrial bioprospecting in the recent years mainly resulted in re-discovery of known antibiotics or their close analogues. Recent data strongly suggest that marine environment represents an untapped source for new biologically active molecules, in particular antibiotics. In this respect, marine bacteria and fungi seem to be the most prominent sources for antibiotic discovery due to their diversity and ability to grow rapidly and sustainably in bioreactors. Other sources, like sponges, corals and other marine animals, can also supply very interesting scaffolds for antibiotic discovery, which can be reproduced through chemical synthesis. Finally, metagenome libraries prepared from diverse marine samples and giving access to the genetic material from unculturable species may also supply new antibiotics.

This special issue of Marine Drugs is dedicated to marine antibiotics, and will be assembled to emphasize the importance of new antibiotic discovery from marine sources by various techniques and from a variety of organisms. I am very happy and honored to serve as a Guest Editor for this special issue, and would like to invite scientists to report their findings or review the recent literature on various aspects of marine antibiotics. I hope that this special issue will encourage other scientists to work on the important topic of the marine antibiotic discovery, and to report their findings in the future issues of Marine Drugs.

Prof. Dr. Sergey B. Zotchev
Guest Editor

Keywords

  • antibiotic
  • marine organisms
  • biosynthesis
  • chemical synthesis
  • antibiotic resistance
  • antibiotic modification
  • metagenome
  • antiviral
  • antibacterial
  • antifungal
  • antihelminthic

Published Papers (11 papers)

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Displaying article 1-11
p. 1071-1086
by , , , , , , , ,  and
Mar. Drugs 2013, 11(4), 1071-1086; doi:10.3390/md11041071
Received: 19 December 2012; in revised form: 22 January 2013 / Accepted: 19 February 2013 / Published: 28 March 2013
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(This article belongs to the Special Issue Marine Antibiotics)
p. 332-349
by , , , , , , , , , ,  and
Mar. Drugs 2013, 11(2), 332-349; doi:10.3390/md11020332
Received: 25 October 2012; in revised form: 21 December 2012 / Accepted: 4 January 2013 / Published: 30 January 2013
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(This article belongs to the Special Issue Marine Antibiotics)
p. 124-135
by , ,  and
Mar. Drugs 2013, 11(1), 124-135; doi:10.3390/md11010124
Received: 14 November 2012; in revised form: 4 December 2012 / Accepted: 25 December 2012 / Published: 10 January 2013
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(This article belongs to the Special Issue Marine Antibiotics)
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p. 40-49
by , , , ,  and
Mar. Drugs 2013, 11(1), 40-49; doi:10.3390/md11010040
Received: 18 October 2012; in revised form: 13 November 2012 / Accepted: 12 December 2012 / Published: 27 December 2012
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(This article belongs to the Special Issue Marine Antibiotics)
p. 1711-1728
by , ,  and
Mar. Drugs 2012, 10(8), 1711-1728; doi:10.3390/md10081711
Received: 12 June 2012; in revised form: 25 July 2012 / Accepted: 1 August 2012 / Published: 15 August 2012
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(This article belongs to the Special Issue Marine Antibiotics)
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p. 1729-1740
by ,  and
Mar. Drugs 2012, 10(8), 1729-1740; doi:10.3390/md10081729
Received: 28 June 2012; in revised form: 26 July 2012 / Accepted: 27 July 2012 / Published: 15 August 2012
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(This article belongs to the Special Issue Marine Antibiotics)
p. 1225-1243
by , ,  and
Mar. Drugs 2012, 10(6), 1225-1243; doi:10.3390/md10061225
Received: 5 April 2012; in revised form: 21 May 2012 / Accepted: 28 May 2012 / Published: 4 June 2012
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(This article belongs to the Special Issue Marine Antibiotics)
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p. 680-689
by , , , ,  and
Mar. Drugs 2011, 9(4), 680-689; doi:10.3390/md9040680
Received: 16 December 2010; in revised form: 15 February 2011 / Accepted: 13 April 2011 / Published: 21 April 2011
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(This article belongs to the Special Issue Marine Antibiotics)
p. 359-368
by , , , , ,  and
Mar. Drugs 2011, 9(3), 359-368; doi:10.3390/md9030359
Received: 7 February 2011; in revised form: 24 February 2011 / Accepted: 11 March 2011 / Published: 17 March 2011
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(This article belongs to the Special Issue Marine Antibiotics)
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p. 2946-2960
by , , ,  and
Mar. Drugs 2010, 8(12), 2946-2960; doi:10.3390/md8122946
Received: 4 November 2010; in revised form: 1 December 2010 / Accepted: 9 December 2010 / Published: 13 December 2010
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(This article belongs to the Special Issue Marine Antibiotics)
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p. 2466-2479
by , , , , , ,  and
Mar. Drugs 2010, 8(9), 2466-2479; doi:10.3390/md8092466
Received: 12 August 2010; in revised form: 25 August 2010 / Accepted: 1 September 2010 / Published: 3 September 2010
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(This article belongs to the Special Issue Marine Antibiotics)
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Last update: 27 February 2014

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