Special Issue "Bioactivity-Focused Syntheses of Marine Natural Products and Congeners"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: 28 February 2014
Dr. Malcom McCulloch
Biomedical Research Centre, Sheffield Hallam University, City Campus, Howard Street, Sheffield, S1 1WB, UK
Phone: + 0114 225 6020
Interests: the natural origins of therapeutic drugs: natural product scaffolds
Marine natural products provide biologically-privileged frameworks for the discovery and development of new therapeutic drugs and biochemical tools. These development processes are frequently supported by synthetic chemistry, including total synthesis, semi-synthesis and congener synthesis. The roles played by synthesis and semi-synthesis include: (1) providing access to adequate quantities of compounds when natural supply is limited; and (2) providing novel analogues for biological evaluation (i.e. develop structure-activity relationships). These efforts can lead to more efficacious compounds, or simplified analogues that retain the desirable biological activity. This Special Issue of Marine Drugs focuses on the use of synthesis to support the discovery and development of marine natural products and congeners as drugs and biochemical tool compounds.
You are cordially invited to submit original papers and review articles to “Bioactivity-Focused Syntheses of Marine Natural Products and Congeners”. Papers describing biological screening of libraries of synthetic or semi-synthetic marine natural product derivatives are encouraged. Manuscripts describing total syntheses, semi-syntheses and analogue syntheses are most welcome provided they include some details of biological evaluations.
Dr Malcolm W. B. McCulloch
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed Open Access monthly journal published by MDPI.
- marine natural product
- total synthesis
- analogue synthesis
- structure-activity relationships
- bioactive natural product derivatives
- bioactivity profiling
- screening of synthetic and semi-synthetic compound libraries
Last update: 31 July 2013