New Advances in Endocrinology and Metabolic Diseases: 2nd Edition

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 2596

Special Issue Editor


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Guest Editor
School of Medicine, Aristotle University of Thessalonik, Thessaloniki, Greece
Interests: hypertension; blood pressure; heart failure; atherosclerosis; cardiovascular medicine; insulin resistance; metabolism; metabolic diseases; lipid metabolism; glucose metabolism
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Special Issue Information

Dear Colleagues,

The editors are grateful to the researchers who contributed to the first volume of this issue (https://www.mdpi.com/journal/life/special_issues/Q55S5UB8W4). We are very pleased to announce the second volume of our Special Issue “New Advances in Endocrinology and Metabolic Diseases".

Metabolic diseases are currently on the rise and represent important risk factors for some of the most common and even fatal conditions, such as cardiovascular diseases (CVDs). Hypertension, dyslipidemia, diabetes mellitus, and especially obesity have reached pandemic dimensions. In addition, they are commonly accompanied by dire comorbidities, such as nonalcoholic fatty liver disease (NAFLD), CVDs, and obesity-associated malignancies. Their increasing prevalence represents a major public health burden.

This Special Issue is devoted to advances in the understanding of the mechanisms underlying metabolic diseases, the inter-relationship between them, and the progress in the prevention as well as treatment of these conditions. We welcome original research articles, reviews, systematic reviews, and case reports encompassing this area of interest.

Dr. Chrysoula Boutari
Guest Editor

Manuscript Submission Information

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Keywords

  • metabolic syndrome
  • dyslipidemia
  • hypertension
  • obesity
  • diabetes mellitus
  • nonalcoholic fatty liver disease
  • cardiovascular diseases

Published Papers (2 papers)

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Review

15 pages, 1305 KiB  
Review
An Emerging Role of Micro- and Nanoplastics in Vascular Diseases
by Seung Eun Lee, Hyun Kyung Yoon, Do Yun Kim, Taek Seung Jeong and Yong Seek Park
Life 2024, 14(2), 255; https://doi.org/10.3390/life14020255 - 16 Feb 2024
Cited by 1 | Viewed by 1275
Abstract
Vascular diseases are the leading causes of death worldwide, and they are attributable to multiple pathologies, such as atherosclerosis, diabetes, and chronic obstructive pulmonary disease. Exposure to various environmental contaminants is associated with the development of various diseases, including vascular diseases. Among environmental [...] Read more.
Vascular diseases are the leading causes of death worldwide, and they are attributable to multiple pathologies, such as atherosclerosis, diabetes, and chronic obstructive pulmonary disease. Exposure to various environmental contaminants is associated with the development of various diseases, including vascular diseases. Among environmental contaminants, micro- and nanoplastics have gained attention as global environmental risk factors that threaten human health. Recently, extensive research has been conducted on the effects of micro- and nanoplastics on various human diseases, including vascular diseases. In this review, we highlight the effects of micro- and nanoplastics on vascular diseases. Full article
(This article belongs to the Special Issue New Advances in Endocrinology and Metabolic Diseases: 2nd Edition)
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18 pages, 1885 KiB  
Review
Postprandial Dysmetabolism and Its Medical Implications
by Emanuel Sasso, Lara Baticic and Vlatka Sotosek
Life 2023, 13(12), 2317; https://doi.org/10.3390/life13122317 - 10 Dec 2023
Viewed by 1072
Abstract
An unbalanced diet increases the risk of developing a variety of chronic diseases and cancers, leading to higher morbidity and mortality rates worldwide. Low-grade systemic chronic inflammation mediated by the activation of the innate immune system is common to all these pathologies. Inflammation [...] Read more.
An unbalanced diet increases the risk of developing a variety of chronic diseases and cancers, leading to higher morbidity and mortality rates worldwide. Low-grade systemic chronic inflammation mediated by the activation of the innate immune system is common to all these pathologies. Inflammation is a biological response of the body and a normal part of host defense to combat the effects of bacteria, viruses, toxins and macronutrients. However, when the innate immune system is constantly activated, it can promote the development of low-grade systemic chronic inflammation, which could play an important role in the development of chronic diseases and cancer. Since most chronic inflammatory diseases are associated with diet, a balanced healthy diet high in anti-inflammatory food components could prevent chronic diseases and cancer. The cells of the body’s immune system produce chemokines and cytokines which can have pro-inflammatory and tumor-promoting as well as anti-inflammatory and tumor-fighting functions. A challenge in the future will be to assess whether polymorphisms in immune-related genes may play a role in promoting pro-inflammatory activity. Thanks to this duality, future research on immune regulation could focus on how innate immune cells can be modified to convert a pro-inflammatory and tumor-friendly microenvironment into an anti-inflammatory and anti-tumor one. This review describes inflammatory responses mediated by the innate immune system in various diseases such as hyperglycemia and/or hyperlipemia, obesity, type II diabetes, cardiovascular disease and cancer. Full article
(This article belongs to the Special Issue New Advances in Endocrinology and Metabolic Diseases: 2nd Edition)
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