Special Issue "Bipolar Disorder in Children and Adolescents"
A special issue of Journal of Clinical Medicine (ISSN 2077-0383).
Deadline for manuscript submissions: closed (20 December 2013)
Dr. Constance M. Moore
Center for Comparative NeuroImaging, University of Massachusetts Medical School, 303 Belmont Street, Worcester, MA 01604, USA
The prevalence of bipolar disorder among children and adolescents is thought to be similar to that among adults: 0.6% to 1.1%. However, there are many differences in the presentation and course of bipolar disorder in youth versus adults: In adults, bipolar disorder frequently presents with a manic episode, and then continues with periods of recovery in-between episodes. Childhood onset bipolar disorder, on the other hand, can present with continuous, mixed manic, rapid cycling states or, conversely, with an initial depressive episode. In addition, children may experience mood episodes differently from those who present in adulthood. For example, children in manic episodes are more likely to be irritable, with aggressive outbursts and behaviors while manic adults tend to be euphoric, or elated, while a depressed child may cry, scratch, and whine constantly, while a depressed adult will appear unhappy, sluggish, and may even exhibit suicidal behavior. Children and adolescents with bipolar illness can experience substantial distress and high degrees of morbidity and mortality. In recent years, the majority of calls to the National Alliance for the Mentally Ill and the National Depressive and Manic Depressive Association have been looking for advice on the diagnosis and treatment of bipolar disorder in very young children. Given the variation in presentation and course, as well as the public health implications for this demographic, it is critical that we as researchers understand the underlying pathophysiology of early-onset bipolar disorder so that we can help develop more effective and targeted treatments for children and adolescents with this illness.
These reviews will cover the following important topics spanning the diagnosis, course, and treatment of early-onset bipolar disorder:
• Risk and/or impact of bipolar disorder in children and adolescents
• Novel diagnostic techniques/development of biomarkers for early-onset bipolar disorder
• Monitoring of symptoms of early-onset bipolar disorder
• Mechanisms of therapy for early-onset bipolar disorder
• Management of patients with early-onset bipolar disorder
Dr. Constance M. Moore
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- bipolar disorder
- children and adolescents
- early onset
- novel therapies
- diagnostic techniques
- clinical care
Article: Cortical Volume Alterations in Conduct Disordered Adolescents with and without Bipolar Disorder
J. Clin. Med. 2014, 3(2), 416-431; doi:10.3390/jcm3020416
Received: 24 December 2013; in revised form: 28 February 2014 / Accepted: 3 March 2014 / Published: 16 April 2014| PDF Full-text (562 KB) | HTML Full-text | XML Full-text
Opinion: Biologism in Psychiatry: A Young Man’s Experience of Being Diagnosed with “Pediatric Bipolar Disorder”
J. Clin. Med. 2014, 3(2), 334-347; doi:10.3390/jcm3020334
Received: 9 December 2013; in revised form: 1 March 2014 / Accepted: 5 March 2014 / Published: 28 March 2014| PDF Full-text (190 KB) | HTML Full-text | XML Full-text
J. Clin. Med. 2014, 3(1), 310-322; doi:10.3390/jcm3010310
Received: 13 December 2013; in revised form: 5 February 2014 / Accepted: 11 February 2014 / Published: 20 March 2014| PDF Full-text (260 KB) | HTML Full-text | XML Full-text
J. Clin. Med. 2014, 3(1), 255-266; doi:10.3390/jcm3010255
Received: 10 December 2013; in revised form: 11 February 2014 / Accepted: 19 February 2014 / Published: 11 March 2014| PDF Full-text (210 KB) | HTML Full-text | XML Full-text
J. Clin. Med. 2014, 3(1), 233-254; doi:10.3390/jcm3010233
Received: 20 December 2013; in revised form: 13 February 2014 / Accepted: 17 February 2014 / Published: 10 March 2014| PDF Full-text (238 KB) | HTML Full-text | XML Full-text
J. Clin. Med. 2014, 3(1), 218-232; doi:10.3390/jcm3010218
Received: 13 December 2013; in revised form: 8 February 2014 / Accepted: 12 February 2014 / Published: 10 March 2014| PDF Full-text (417 KB) | HTML Full-text | XML Full-text
Review: Clinical Guidelines on Long-Term Pharmacotherapy for Bipolar Disorder in Children and Adolescents
J. Clin. Med. 2014, 3(1), 135-143; doi:10.3390/jcm3010135
Received: 9 December 2013; in revised form: 27 December 2013 / Accepted: 9 January 2014 / Published: 21 January 2014| PDF Full-text (176 KB) | HTML Full-text
Last update: 6 August 2013