2nd Edition: Molecular Mechanisms Regulating Osteoclastogenesis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 2187
Special Issue Editor
Interests: osteoimmunology; osteoclast; osteoblast; bone remodeling; bone diseases; cardiovascular disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bone remodeling is a tightly regulated process involving the interplay among osteoclasts, osteoblasts, and osteocytes. Osteoclasts are the bone resorbing cells arising from the fusion of monocyte/macrophage precursors. Osteoclastogenesis is primarily supported by osteoblasts but also by other cells of the bone marrow microenvironment, such as immune cells, adipocytes, and endothelial cells. Osteoclastogenesis is a finely controlled process, and its deregulation is related to different bone diseases; thus, the deepening of the mechanisms regulating osteoclast formation can be useful for identifying new pharmacological targets.
This special issue encourages submissions of full-review or original research papers, and perspectives on the biological, functional, and mechanistic question(s) being addressed.
Dr. Giacomina Brunetti
Guest Editor
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Keywords
- osteoclasts
- osteoimmunology
- T cells
- B cells
- bone marrow microenvironment
- osteoblasts
- growth factors
- cytokines
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