Special Issue "Biodegradable Magnesium Alloys and Implants"
Deadline for manuscript submissions: 1 April 2014
Dr. Mihriban O. Pekguleryuz
Department of Mining and Materials Engineering, McGill University Montreal, Quebec, Canada
Interests: light metals; aluminum, magnesium; alloy development; biodegradable magnesium implants
Magnesium biomaterials are emerging as important candidates for bio-resorbable implant applications. Because magnesium biodegrades via corrosion by the body fluids, the stimulus for hyperplasia is removed and the tendency to restenosis is minimized, while the substrate for local tissue irritation is eliminated. Magnesium has an advantage over biodegradable polymeric stents in that it can have smaller mass for equal mechanical performance and can be better visualized in CT scans. Biodegradable stents have been successfully used in pediatric patients with congenital heart disease and other clinical trials with magnesium alloys have been undertaken. Furthermore, Mg offers key advantage as the deployment material for drug delivery and gene therapy. Research now focuses on developing improved Mg alloys with lower bio-corrosion rates without creating potential toxicity problems related to some alloying elements. Eventual use in biomedical devices also necessitates optimization of the alloys for mechanical performance.
Dr. Mihriban Pekguleryuz
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- magnesium alloys
- biodegradable magnesium implants
- biocorrosion and biocompatibility
- bio absorbable metallic stents
- orthopaedic metallic implants
- toxicity and cell viability
Article: In Vitro Corrosion and Cytocompatibility of ZK60 Magnesium Alloy Coated with Hydroxyapatite by a Simple Chemical Conversion Process for Orthopedic Applications
Int. J. Mol. Sci. 2013, 14(12), 23614-23628; doi:10.3390/ijms141223614
Received: 27 September 2013; in revised form: 23 October 2013 / Accepted: 4 November 2013 / Published: 3 December 2013| Download PDF Full-text (1660 KB) | Download XML Full-text
Review: Bioresorbable Drug-Eluting Magnesium-Alloy Scaffold for Treatment of Coronary Artery Disease
Int. J. Mol. Sci. 2013, 14(12), 24492-24500; doi:10.3390/ijms141224492
Received: 21 October 2013; in revised form: 3 December 2013 / Accepted: 12 December 2013 / Published: 16 December 2013| Download PDF Full-text (551 KB) | Download XML Full-text
Int. J. Mol. Sci. 2014, 15(2), 2959-2970; doi:10.3390/ijms15022959
Received: 26 October 2013; in revised form: 2 January 2014 / Accepted: 16 January 2014 / Published: 20 February 2014| Download PDF Full-text (3010 KB)
Last update: 7 November 2013