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Int. J. Mol. Sci. 2014, 15(5), 7639-7650; doi:10.3390/ijms15057639
Article

Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions

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Received: 27 February 2014; in revised form: 20 March 2014 / Accepted: 16 April 2014 / Published: 5 May 2014
(This article belongs to the Special Issue Biodegradable Magnesium Alloys and Implants)
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Abstract: Magnesium based implants could revolutionize applications where orthopedic implants such as nails, screws or bone plates are used because they are load bearing and degrade over time. This prevents a second surgery to remove conventional implants. To improve the biocompatibility we studied here if and for how long a pre-incubation of the material under cell culture conditions is favorable for cell attachment and proliferation. For two materials, Mg and Mg10Gd1Nd, we could show that 6 h pre-incubation are already enough to form a natural protective layer suitable for cell culture.
Keywords: magnesium implants; natural corrosion protection; pre-incubation; biocompatibility magnesium implants; natural corrosion protection; pre-incubation; biocompatibility
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Willumeit, R.; Möhring, A.; Feyerabend, F. Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions. Int. J. Mol. Sci. 2014, 15, 7639-7650.

AMA Style

Willumeit R, Möhring A, Feyerabend F. Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions. International Journal of Molecular Sciences. 2014; 15(5):7639-7650.

Chicago/Turabian Style

Willumeit, Regine; Möhring, Anneke; Feyerabend, Frank. 2014. "Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions." Int. J. Mol. Sci. 15, no. 5: 7639-7650.


Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert