Amides
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (31 August 2020) | Viewed by 37123
Special Issue Editors
Interests: inflammation; oxidative stress; biochemistry; pharmacology; molecular biology
Special Issues, Collections and Topics in MDPI journals
Interests: veterinary pharmacology; veterinary toxicology; animal models of inflammation and neuroinflammation; neurotoxicology; animal science
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We invite you to submit your valuable and latest research outcomes for publication in the Special Issue entitled “Amides” for the International Journal of Molecular Sciences—IJMS (MDPI). The Special Issue will focus on the role and effectiveness of “Autacoid local injury antagonist amides” (ALIAmides) in health promotion and wellbeing.
ALIAmides are a family of endogenous bioactive acyl ethanolamides acting as bioregulators under inflammatory and oxidative stress conditions; their levels are principally regulated by enzymes responsible for their formation and degradation. N-palmitoylethanolamide (PEA) is considered to be the parent molecule of ALIAmides; it is known for its anti-inflammatory, analgesic and neuroprotective properties, and it exerts its anti-inflammatory effect by down-regulating mast-cell degranulation via an “Autacoid Local Inflammation Antagonism”(ALIA) effect. These endogenous bioactive lipids play a role in a number of biological processes, including pain, metabolism, and inflammation. The topic will include research studies on ALIAmides or their analogs, as plausible therapeutic strategies in the treatment of several inflammatory conditions such as chronic pain, tissue inflammation, chronic kidney disease, inflammatory bowel diseases, arthritis, osteoarthritis, and others.
Research articles collecting data from both in vitro and in vivo investigations are welcome. Papers published in IJMS are encouraged to include results at molecular level. In addition, review articles reporting about the mode of actions of ALIAmides would complete the topic.
Dr. Daniela Impellizzeri
Dr. Rosalia Crupi
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Inflammation
- ALIAmides
- Pain
- Oxidative stress
- Mechanism of action
- Molecular level