Reproductive Immunology: New Insights into Physiology and Pathophysiology of Pregnancy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 10288
Special Issue Editors
Interests: immunology; reproductive immunology; pregnancy; autoimmune; inflammatory disorders
Interests: blocking factor; habitual abortion; progesterone; trophoblasts; decidua; natural killer cells
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Though several underlying pathologies have been identified, 15% of female infertilities remain unexplained. Treatment options are still scarce. However, some of the problems can be solved through assisted reproductive technologies. Deficient endometrium receptivity, inadequate development, or poor implantation capacity of the embryo represent the most common causes of female infertility.
Immune cells play crucial roles in maintaining fertility and securing a successful pregnancy outcome, by influencing follicular/embryo development and endometrial receptivity, including vascular maternal adaptation.
The comprehension of the uterine and ovarian immune cellular and molecular mechanisms is essential for developing more efficient ways not only to treat reproductive issues but also to define the indications for immune checkpoints as a novel therapeutic option in reproductive clinical practice.
This Special Issue aims to highlight the emerging areas of research within the reproductive immunology field and contribute to a better understanding of the immune cellular and molecular mechanisms, together with the observed clinical outcomes, which could be essential for defining the indications for immune therapeutic options in managing infertility and pregnancy pathologies.
Dr. Marie-Pierre Piccinni
Prof. Dr. Julia Szekeres-Bartho
Prof. Dr. Sandra Maria Blois
Guest Editors
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