Advances in Molecular Mechanisms of Neurodegeneration and Neuroinflammation
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 22
Special Issue Editors
Interests: molecular biology; neuroinflammation; pharmacology; inflammation; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Interests: neuroinflammation; neurodegeneration; inflammation; oncology; brain tumor
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons and cognitive and/or motor impairments. Mounting evidence has revealed that neuroinflammation plays a pivotal role in the onset and progression of these disorders, interacting closely with cellular and molecular events such as oxidative stress, protein aggregation, mitochondrial dysfunction, and impaired autophagy.
This Special Issue, "Advances in Molecular Mechanisms of Neurodegeneration and Neuroinflammation", aims to explore recent breakthroughs in understanding the intricate molecular pathways involved in neurodegenerative processes and inflammatory responses in the central nervous system. We invite original research articles, reviews, and short communications that focus on, but are not limited to, the roles of glial cell activation, immune signaling cascades, non-coding RNAs, epigenetic regulation, and novel therapeutic targets modulating these mechanisms.
Submissions involving in vitro, in vivo, or computational models, as well as translational studies investigating potential biomarkers or pharmacological interventions, are welcome. This Special Issue seeks to provide a platform for the latest findings that could foster the development of innovative therapeutic strategies to prevent or delay neurodegeneration and its associated pathologies.
Dr. Marika Lanza
Dr. Giovanna Casili
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neuroinflammation
- neurodegeneration
- mitochondrial dysfunction
- oxidative stress
- metabolomics
- therapeutic strategies
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