Molecular Circuits Regulating Sleep and Wakeful Consciousness
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 29556
Special Issue Editors
Interests: sleep; motivation; arousal; sleep function; neural circuits; opto-biology/pharmacology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The sleep field has recently witnessed an exponential increase in the understanding of brain circuitries regulating sleep/wake behavior. However, it remains puzzling that brain circuits’ switching occurs within seconds, while sleep regulation (i.e., the process of the accumulation/dissipation of sleep need) takes hours. The teleological problem of sleep regulation and function arises from the presumption of sleep’s evolution from a default state of waking. Humans are likely biased towards this presumption by the egocentricity of waking consciousness. The goal of the Special Issue is to gather original research and review articles relevant to the control of non-rapid eye movement (non-REM), REM sleep, or wakeful consciousness. We are especially seeking contributions that shed light on mechanisms underlying key aspects of the sleep states, such as sleep need; the circadian, ultradian, or behavioral gating of sleep; and REM sleep homeostasis. We are open to articles that use innovative techniques to study the detailed circuit and synaptic basis of sleep/wake control, for example, electrophysiological recording or imaging used in combination with pharmacologic or the genetically driven perturbation of defined sets of neurons or glial cells in all animals that have the ability to sleep or exhibit a sleep-like behavior. We also welcome studies on the molecular profiling of sleep and wake states or the crosstalk between sleep and peripheral physiological systems (e.g., immune system or metabolism), as well as studies about physical and chemical factors that influence sleep and wakefulness.
Prof. Dr. Michael Lazarus
Dr. Wang Yi-Qun
Guest Editors
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Keywords
- sleep
- sleep function
- glia–neuron interaction
- molecular circuits
- sleep homeostasis
- arousal
- slow-wave sleep
- REM sleep
- physical or chemical sleep/wake factors
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