Special Issue "Next Generation DNA Sequencing"

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A special issue of Genes (ISSN 2073-4425).

Deadline for manuscript submissions: closed (31 May 2010)

Special Issue Editor

Guest Editor
Dr. Paul Richardson
PRC LLC, 25 Amber Lane, Lafayette CA 94549, USA
E-Mail: paulrichardson07@gmail.com
Phone: +1 (925) 301-5460
Interests: microbial genomics; technology development; infectious diseases; gene expression

Special Issue Information

Dear Colleagues,

We are currently in the midst of a revolution in DNA sequencing that promises unprecedented access to genetic data. Next Generation Sequencing (NGS) and follow-on technologies such as single molecule sequencing (next-next gen or 3rd generation) instruments and methods are advancing rapidly. These advances open the door to new applications for sequencing such as large-scale association studies, comparative genomics, metagenomics and the study of ancient DNA. These technologies have also been used in chromatin immunoprecipitation studies to determine DNA binding sites and quantitative RNA expression analysis by sequencing. These instrument platforms create unique challenges both upstream and downstream of the data generation. Improved methods for library construction and amplification strategies to produce more uniform and complete coverage are required. Methods are also evolving for the processing and analysis of extremely large numbers (often short) reads to better understand quality, improve alignments and generate whole-genome assemblies. Given the huge impact of these developments, a special issue of the journal Genes is being issued to explore the methods and applications of these new sequencing technologies. Authors are encouraged to submit original manuscripts describing utilization of Next Generation Sequencing to answer scientific questions. Also encouraged are papers describing new methods or instruments, and reviews or comparisons of Next Generation Sequencing technologies as well as manuscripts dealing with bioinformatic methods of analysis.

Dr. Paul Richardson
Guest Editor

Keywords

  • DNA Sequencing
  • next generation sequencing
  • single molecule sequencing
  • massively parallel sequencing
  • metagenomics
  • ChiP-Seq
  • ancient DNA
  • digital gene expression

Published Papers (11 papers)

by
Genes 2010, 1(3), 385-387; doi:10.3390/genes1030385
Received: 21 October 2010; Accepted: 26 October 2010 / Published: 27 October 2010
Show/Hide Abstract | Cited by 2 | PDF Full-text (24 KB) | XML Full-text

by , , , , , ,  and
Genes 2010, 1(3), 371-384; doi:10.3390/genes1030371
Received: 21 September 2010; in revised form: 5 October 2010 / Accepted: 11 October 2010 / Published: 26 October 2010
Show/Hide Abstract | Cited by 11 | PDF Full-text (2192 KB) | XML Full-text | Supplementary Files
abstract graphic

by  and
Genes 2010, 1(2), 317-334; doi:10.3390/genes1020317
Received: 17 August 2010; Accepted: 20 September 2010 / Published: 27 September 2010
Show/Hide Abstract | Cited by 4 | PDF Full-text (378 KB) | XML Full-text

by , , , ,  and
Genes 2010, 1(2), 294-307; doi:10.3390/genes1020294
Received: 27 July 2010; in revised form: 30 August 2010 / Accepted: 14 September 2010 / Published: 14 September 2010
Show/Hide Abstract | Cited by 15 | PDF Full-text (434 KB) | XML Full-text

by ,  and
Genes 2010, 1(2), 263-282; doi:10.3390/genes1020263
Received: 1 June 2010; in revised form: 18 August 2010 / Accepted: 31 August 2010 / Published: 13 September 2010
Show/Hide Abstract | Cited by 3 | PDF Full-text (513 KB) | XML Full-text

by  and
Genes 2010, 1(2), 227-243; doi:10.3390/genes1020227
Received: 31 May 2010; in revised form: 20 July 2010 / Accepted: 23 July 2010 / Published: 28 July 2010
Show/Hide Abstract | Cited by 21 | PDF Full-text (321 KB) | XML Full-text

by , , , ,  and
Genes 2010, 1(2), 210-226; doi:10.3390/genes1020210
Received: 11 May 2010; in revised form: 8 July 2010 / Accepted: 20 July 2010 / Published: 21 July 2010
Show/Hide Abstract | Cited by 4 | PDF Full-text (1273 KB) | XML Full-text | Supplementary Files
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by ,  and
Genes 2010, 1(2), 143-165; doi:10.3390/genes1020143
Received: 3 May 2010; in revised form: 22 June 2010 / Accepted: 28 June 2010 / Published: 1 July 2010
Show/Hide Abstract | Cited by 2 | PDF Full-text (629 KB) | XML Full-text
abstract graphic

by  and
Genes 2010, 1(1), 85-101; doi:10.3390/genes1010085
Received: 28 April 2010; in revised form: 1 June 2010 / Accepted: 3 June 2010 / Published: 4 June 2010
Show/Hide Abstract | Cited by 7 | PDF Full-text (188 KB) | XML Full-text

by , ,  and
Genes 2010, 1(1), 70-84; doi:10.3390/genes1010070
Received: 30 April 2010; in revised form: 1 June 2010 / Accepted: 3 June 2010 / Published: 3 June 2010
Show/Hide Abstract | Cited by 13 | PDF Full-text (651 KB) | XML Full-text

by  and
Genes 2010, 1(1), 38-69; doi:10.3390/genes1010038
Received: 15 April 2010; in revised form: 20 May 2010 / Accepted: 21 May 2010 / Published: 25 May 2010
Show/Hide Abstract | Cited by 8 | PDF Full-text (526 KB) | XML Full-text
abstract graphic

Last update: 25 February 2014

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