Special Issue "Junk DNA' is not Junk"

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A special issue of Genes (ISSN 2073-4425).

Deadline for manuscript submissions: closed (15 May 2012)

Special Issue Editor

Guest Editor
Prof. Dr. Mary E. Delany
Department of Animal Science, The University of California, Davis, USA
Website: http://animalscience.ucdavis.edu/faculty/delany/
E-Mail: medelany@ucdavis.edu
Phone: +1 530 752 0233
Fax: +1 530 752 0175

Special Issue Information

Dear Colleagues,

Since the late Susumu Ohno first introduced the phrase “junk DNA” in 1972 (“So Much Junk DNA in Our Genome”, Brookhaven Symposium on Biology 23:366-370) the concept has captured the imagination of scientists and non-scientists alike leading to much research as well as debate.  Ohno’s original hypothesis regarding the origin and evolutionary significance of “junk DNA” has been modified and refined over the last four decades benefitting from recent comparative and functional genomics analyses and as influenced by the large-scale bioinformatics analysis of sequences. Many have argued we must abandon Ohno’s terminology, but yet it persists, largely because it remains an interesting conceptual framework to explore given the relative enormity of sequence content in the non-protein-coding category and the finding that gene numbers appear surprisingly similar among vertebrates while non-coding sequences range from being widely variable to unexpected conservation.

This special issue seeks to cover a broad range of topics on the types, functions, conservation, evolution and ultimately the biological significance of “junk DNA” broadly defined as “non-protein-coding sequence” found within and among genomes.  We encourage contributions covering the diversity of species. We welcome scientific perspectives, reviews and original research papers on the topic of “junk DNA” and its biological significance.

Prof. Dr. Mary E. Delany
Guest Editor

Keywords

  • Junk DNA
  • non-coding DNA
  • genome evolution
  • telomeres
  • centromeres
  • functional RNA
  • siRNA
  • piRNA
  • lincRNA
  • miRNA
  • snoRNA
  • rRNA
  • tRNA
  • pseudogenes
  • regulatory elements
  • introns
  • transposons
  • retrotransposons
  • repetitive DNA
  • Heterochromatin
  • ENCODE

Published Papers (9 papers)

Genes 2012, 3(4), 651-670; doi:10.3390/genes3040651
Received: 16 May 2012; in revised form: 17 August 2012 / Accepted: 25 September 2012 / Published: 15 October 2012
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Genes 2012, 3(4), 634-650; doi:10.3390/genes3040634
Received: 25 July 2012; in revised form: 11 September 2012 / Accepted: 25 September 2012 / Published: 12 October 2012
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Genes 2012, 3(3), 492-504; doi:10.3390/genes3030492
Received: 1 June 2012; in revised form: 18 July 2012 / Accepted: 24 July 2012 / Published: 2 August 2012
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Genes 2012, 3(3), 461-480; doi:10.3390/genes3030461
Received: 25 June 2012; in revised form: 19 July 2012 / Accepted: 21 July 2012 / Published: 26 July 2012
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Genes 2012, 3(3), 444-460; doi:10.3390/genes3030444
Received: 16 May 2012; in revised form: 4 July 2012 / Accepted: 5 July 2012 / Published: 23 July 2012
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Genes 2012, 3(3), 409-422; doi:10.3390/genes3030409
Received: 19 May 2012; in revised form: 19 June 2012 / Accepted: 25 June 2012 / Published: 12 July 2012
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Genes 2012, 3(3), 344-360; doi:10.3390/genes3030344
Received: 15 May 2012; in revised form: 14 June 2012 / Accepted: 25 June 2012 / Published: 29 June 2012
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Genes 2012, 3(1), 176-190; doi:10.3390/genes3010176
Received: 2 February 2012; in revised form: 28 February 2012 / Accepted: 29 February 2012 / Published: 8 March 2012
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Genes 2012, 3(1), 167-175; doi:10.3390/genes3010167
Received: 14 January 2012; in revised form: 21 February 2012 / Accepted: 28 February 2012 / Published: 7 March 2012
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Last update: 25 February 2014

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