Genes 2012, 3(1), 176-190; doi:10.3390/genes3010176
Review

Molecular Functions of Long Non-Coding RNAs in Plants

* email and email
Received: 2 February 2012; in revised form: 28 February 2012 / Accepted: 29 February 2012 / Published: 8 March 2012
(This article belongs to the Special Issue Junk DNA' is not Junk)
View Full-Text   |   Download PDF [187 KB, uploaded 8 March 2012]
Abstract: The past decade has seen dramatic changes in our understanding of the scale and complexity of eukaryotic transcriptome owing to the discovery of diverse types of short and long non-protein-coding RNAs (ncRNAs). While short ncRNA-mediated gene regulation has been extensively studied and the mechanisms well understood, the function of long ncRNAs remains largely unexplored, especially in plants. Nevertheless, functional insights generated in recent studies with mammalian systems have indicated that long ncRNAs are key regulators of a variety of biological processes. They have been shown to act as transcriptional regulators and competing endogenous RNAs (ceRNAs), to serve as molecular cargos for protein re-localization and as modular scaffolds to recruit the assembly of multiple protein complexes for chromatin modifications. Some of these functions have been found to be conserved in plants. Here, we review our current understanding of long ncRNA functions in plants and discuss the challenges in functional characterization of plant long ncRNAs.
Keywords: long non-coding RNA; RNA-seq; natural miRNA target mimic; chromatin modifier
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Zhu, Q.-H.; Wang, M.-B. Molecular Functions of Long Non-Coding RNAs in Plants. Genes 2012, 3, 176-190.

AMA Style

Zhu Q-H, Wang M-B. Molecular Functions of Long Non-Coding RNAs in Plants. Genes. 2012; 3(1):176-190.

Chicago/Turabian Style

Zhu, Qian-Hao; Wang, Ming-Bo. 2012. "Molecular Functions of Long Non-Coding RNAs in Plants." Genes 3, no. 1: 176-190.


Genes EISSN 2073-4425 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert