Special Issue "Radiation-Related Cancer 25 Years After Chernobyl"
A special issue of Genes (ISSN 2073-4425).
Deadline for manuscript submissions: closed (31 October 2011)
Prof. Dr. Horst Zitzelsberger
Research Unit of Radiation Cytogenetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstr. 1, 85764 Neuherberg, Germany
Phone: +49 89 318 73421
Fax: +49 89 318 72873
Interests: cytogenetics; chromosome aberrations; cancer cytogenetics; molecular cytogenetics; radiation biology; thyroid cancer; radiation-induced carcinogenesis; positional cloning of chromosomal breakpoints
The 26th of April, 2011, marks the 25th anniversary of the Chernobyl accident in northern Ukraine, the largest nuclear plant accident in history. As a consequence, approximately five million people were exposed to the radioactive fallout in the Russian Federation, Ukraine and Belarus. This nuclear disaster along with the atomic bomb explosions in Japan 65 years ago, called to mind the carcinogenic potential of ionizing radiation and its long-term health effects that arise in exposed populations. One of the most surprising health effects of the Chernobyl accident was the appearance and magnitude of cases of thyroid cancer in children that lived in the heavily contaminated areas. In the decades following the accident many researchers have looked at the biological effects occuring in cells that were exposed to radiation in order to understand the molecular mechanisms associated with radiation-related cancer. Although evidence of radiation-induced DNA damage, such as the induction of chromosome aberrations exists, there are only few indications of radiation-specific molecular markers in these tumors. In order to gain a better understanding of the specific actions of ionizing radiation in tumor development, it also might be helpful to identify radiation-specific gene alterations in tumors developed after medical irradiation. To mark the 25th anniversary of the Chernobyl accident, a special issue of the journal Genes will be issued in order to shed light on knowledge about molecular mechanisms in radiation-related cancer. Authors are encouraged to submit original research articles and reviews reporting findings from studies on cancers of radiation-exposed cohorts. Also welcome are papers on animal or cell culture studies modeling the radiocarcinogenic process. This special issue is intented to provide an overview on current knowledge in the research of radiaton-related cancer.
Prof. Dr. Horst Zitzelsberger
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 300 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- post-Chernobyl cancer
- cancers from radiation-exposed cohorts
- radiation-induced cancers in animals
- radiation-transformed cell models
- radiation markers in tumors
- mechanisms of radiocarcinogenesis
Genes 2011, 2(2), 374-383; doi:10.3390/genes2020374
Received: 14 April 2011; in revised form: 24 May 2011 / Accepted: 30 May 2011 / Published: 31 May 2011| Download PDF Full-text (268 KB) | Download XML Full-text
Genes 2011, 2(2), 384-393; doi:10.3390/genes2020384
Received: 6 April 2011; in revised form: 18 May 2011 / Accepted: 27 May 2011 / Published: 31 May 2011| Download PDF Full-text (298 KB) | Download XML Full-text
Genes 2011, 2(3), 397-419; doi:10.3390/genes2030397
Received: 23 April 2011; in revised form: 23 May 2011 / Accepted: 16 June 2011 / Published: 28 June 2011| Download PDF Full-text (770 KB) | Download XML Full-text
Genes 2011, 2(4), 1033-1049; doi:10.3390/genes2041033
Received: 16 September 2011; in revised form: 1 November 2011 / Accepted: 4 November 2011 / Published: 29 November 2011| Download PDF Full-text (325 KB) | Download XML Full-text
Review: Discriminating Gene Expression Signature of Radiation-Induced Thyroid Tumors after Either External Exposure or Internal Contamination
Genes 2012, 3(1), 19-34; doi:10.3390/genes3010019
Received: 3 November 2011; in revised form: 6 December 2011 / Accepted: 9 December 2011 / Published: 21 December 2011| Download PDF Full-text (889 KB) | Download XML Full-text |
Review: Biological Complexities in Radiation Carcinogenesis and Cancer Radiotherapy: Impact of New Biological Paradigms
Genes 2012, 3(1), 90-114; doi:10.3390/genes3010090
Received: 30 December 2011; in revised form: 7 January 2012 / Accepted: 13 January 2012 / Published: 20 January 2012| Download PDF Full-text (223 KB) | Download XML Full-text
Genes 2012, 3(2), 248-260; doi:10.3390/genes3020248
Received: 28 February 2012; in revised form: 7 March 2012 / Accepted: 22 March 2012 / Published: 29 March 2012| Download PDF Full-text (106 KB) | Download XML Full-text |
Communication: The Chernobyl Tissue Bank — A Repository for Biomaterial and Data Used in Integrative and Systems Biology Modeling the Human Response to Radiation
Genes 2012, 3(2), 278-290; doi:10.3390/genes3020278
Received: 2 April 2012; in revised form: 26 April 2012 / Accepted: 29 April 2012 / Published: 9 May 2012| Download PDF Full-text (202 KB) | Download XML Full-text
Last update: 24 October 2012