Special Issue "Evolution and Structure of Proteins and Proteomes"

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Population and Evolutionary Genetics and Genomics".

Deadline for manuscript submissions: closed (31 May 2018)

Special Issue Editors

Guest Editor
Dr. David Liberles

Department of Biology, Temple University, Philadelphia, PA, USA
Website | E-Mail
Interests: comparative genomics; protein evolution; computational evolutionary systems biology; gene duplication
Guest Editor
Dr. Ashley Teufel

Department of Integrative Biology, University of Austin Texas, Austin, TX, USA
Website | E-Mail
Interests: protein evolution; gene duplication; computational biology; virology

Special Issue Information

Dear Colleagues, 

The evolution of proteins and proteomes is governed by a wealth of interacting processes, spanning from the population level to the atomic level. When a mutation appears in a protein coding sequence, its ultimate fate in a population depends, in part, on its effects on functional sites, folding and stability, and expression. Even subtle modifications to any of these components can have downstream effects on systems-level processes that influence individual fitness. Although these molecular processes occur within an individual, their evolutionary consequences are determined by the population into which they are cast. In this Special Issue, we encourage the contribution of review articles and original research papers that examine the evolution and structure of proteins and proteomes through a merger of biophysics, systems biology, evolutionary, and population genetic frameworks.

Dr. David Liberles
Dr. Ashley Teufel
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • protein
  • proteome
  • evolution
  • molecular function
  • biophysical models
  • evolutionary systems biology
  • biological networks

Published Papers

There is no accepted submissions to this special issue at this moment.
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