Special Issue "Biomarkers in Blood"
A special issue of Diagnostics (ISSN 2075-4418).
Deadline for manuscript submissions: closed (25 March 2015)
Prof. Dr. Ludmilla A. Morozova-Roche
Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, SE 90781, Sweden
Fax: +46 90 786 9795
Interests: amyloid; protein folding; neurodegeneration; inflammation; amyloid diseases
The issue "Biomarkers in Blood" will be focused on the diagnostics of plethora of pathologies, including such widely spread ailments as cancer, neurodegenerative Alzheimer’s, Parkinson’s and other diseases as well as other pathological conditions, by using biomarkers in the blood. Due to growing elderly population these diseases are on the rise in the modern society and combatting them is a global issue. The early or even pre-clinical diagnostics of pathological conditions at the stage when the clinical symptoms are not obvious would be of significant therapeutic value and would enable to administer protective or preventive treatments at an earlier stage. The molecular constitution of blood can be highly representative of the physiological state of an individual. Patient blood serum analyses are potentially minimally invasive and cheap means of both early disease detection and the convenient monitoring of disease response to therapeutic intervention. These approaches are tightly aligned with the concept of personalised healthcare. Over last years a range of new robust diagnostic assays underpinning the presymptomatic detection of pathological conditions were established as well as a range of new biomarkers associated with the disease pathology were discovered. The biodiagnostics is a rapidly expanding field and yet many problems need to be solved. Experience shows that candidate biomarkers may fail to demonstrate their clinical utility, which can be because they are genuinely not relevant to the disease, or their validation has been limited to a subset of patients to whom they are relevant, or the technical limitations of the detection methods.
The present issue aims at bringing a collection of research and reviewer articles together to summarize a state of the art, problems and future directions in the biomarker and biodiagnostics field based on the blood analysis. Your contribution is very welcome!
Prof. Dr. Ludmilla Morozova-Roche
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- biosensor assay
- blood analysis
- presymptomatic detection
- disease monitoring
- neurodegenerative diseases