Special Issue "Improving Enzyme-Based Sensors with Innovative Materials and Techniques"

A special issue of Chemosensors (ISSN 2227-9040).

Deadline for manuscript submissions: closed (31 January 2017)

Special Issue Editors

Guest Editor
Prof. Dr. H. James Harmon

Emeritus Professor Physics Department, Oklahoma State University, Stillwater, OK 74078-3072, USA
Website | E-Mail
Interests: enzyme-based real-time chemical sensors; receptor-based real-time biological sensors; optical sensors; porphyrins and porphyrin-based sensors; nanolayer thin-film sensors; absorbance/fluorescence/evanescent spectroscopy; multiphoton absorbance; photocatalytic degradation of compounds by porphyrins
Guest Editor
Dr. Brandy J. Johnson

Center for Bio/Molecular Science and Engineering, Code 6900, US Naval Research Laboratory, Washington, DC 20375, USA
Website | E-Mail
Interests: chemical sensors; biosensors; distributed sensing; surface chemistry; indicator development; fluorescence

Special Issue Information

Dear Colleagues,

Enzyme-based chemical sensing is the basis for a large and well-established field of research, ranging from commercial products, such as blood glucose monitors, to developments in protein engineering. Advances in materials and techniques offer the potential to extend the applicability of enzyme-based sensing by providing enhancements in enzyme performance or in overall utility. Some examples include improvements in enzyme sensitivity and stability, enhanced control over enzyme orientation, co-localized enzyme and/or cofactor immobilization for cascade processes, and enhanced reporter performance. These types of advances can be driven by the materials used; for example, inorganic nanoparticles, nanowires, and graphene have been shown to improve electron transfer kinetics for redox enzymes in electrochemical sensing schemes; electrospun nanofibers offer high surface area and controlled porosity to enzyme-based sensing approaches. These developments may also be driven by emerging techniques; co-entrapment of enzymes and dye reporters within nanoparticles can provide enhanced detection in lateral flow assays. Overall, the types of innovative materials and techniques currently under development offer the potential to address shortfalls in sensitivity, stability, and selectivity for enzyme-based sensing strategies, making them more suited for use in complex and changing environments. This Special Issue highlights developments providing new or extended capabilities in enzyme-based sensing for environmental and health related applications.

Prof. Dr. H. James Harmon
Dr. Brandy J. Johnson
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 350 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.



  • enzyme-based sensing
  • enzyme cascade
  • immobilization
  • orientation
  • analysis techniques
  • nanomaterials

Published Papers

There is no accepted submissions to this special issue at this moment.
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