ROS-Mediated Therapeutic Approaches for Cells
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (31 August 2021) | Viewed by 3342
Special Issue Editor
Interests: nanoparticle-based drug targeting against cancer; nanomedicine-based drug delivery system across blood-brain barrier; nanomedicine for Alzheimer's disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Reactive oxygen species (ROS), in a chemically reactive state, are peroxides, superoxide, hydroxyl radical, singlet oxygen and alpha-oxygen, etc. They have been extensively investigated in the field of cellular metabolism, cell therapy, cancer cell treatment and molecular targeting. Especially, ROS are known to have deep relationship with various kinds of disease, i.e., they are involved in pathogenesis, progression of symptoms and cell death. ROS can be acted as a double-edged sword, i.e., they involved in proliferation, migration and metabolism of cells even though they are by-products of cellular oxygen metabolism. Consequently, ROS generation in normal cells, stem cells and/or various disease cells can be applied as a target for therapeutic purposes. For example, ROS overproduction and imbalance of homeostasis in cancer cells induces apoptosis and/or necrosis, and then death of cancer cells. Then, many scientists have been tried to invent molecular targets and/or chemical agents for ROS production of cancer cells. Otherwise, some of them investigated ideal conditions for proliferation or induction of normal cells, stem cells and therapeutic cells. ROS generation and therapeutic approaches should be still explored for overcoming of various diseases.
Some of the topics around ROS generation in the cells and their therapeutic approaches to be tackled in this Special Issue include but are not limited to:
- Cellular mechanism of ROS production;
- ROS-producing agents and their cellular responses;
- ROS-related cell therapy;
- ROS-mediated cancer cell treatment;
- Disease diagnosis using ROS-sensitive mechanism.
Dr. Young-IL Jeong
Guest Editor
Manuscript Submission Information
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Keywords
- Cellular reactive oxygen species (ROS) metabolism
- Cellular oxidative stress
- ROS-mediated cell therapy
- ROS-related immunological responses
- ROS-producing chemical agents
- Therapeutic approaches of various disease cells using ROS
- Disease diagnosis using ROS-related mechanism
