Special Issue "Biocompatible Materials"
Deadline for manuscript submissions: 15 December 2018
Prof. Dr. Giovanni Vozzi
Research Center “E. Piaggio” and Department of Ingegneria dell’Informazione, University of Pisa, via Diotisalvi 2, 56122 Pisa, Italy
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Interests: Design of new functionalization methodologies of biomaterials; Mechanical, chemical and cell characterization of novel biomaterials; Development of new micro- and nano-fabrication techniques; Fabrication of bioreactors; Development of in-silico cell models; Acquisition and processing of electromyographic signal; Tissue engineering and regenerative medicine; Biofabrication
I am pleased to announce an upcoming Special Issue focusing on biocompatible materials. It my pleasure to invite you and members of your research team to submit an article for this Special Issue.
Biocompatible material is now defined as a substance, or a combination of substances, which has been engineered and processed to interact with components of living systems with an appropriate response in a specific application.
We invite authors to contribute original research or reviews describing detailed experimental studies, investigations and novel developments dealing with important issues facing the synthesis, design, fabrication and characterization of biocompatible material for clinical applications, including, but without being limited to diagnosis, therapies, regenerative medicine and implantable devices.Prof. Dr. Giovanni Vozzi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Regenerative Medicine
- Medical Devices
- Drug Delivery
- Medical Devices
- Diagnostic Systems
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
The type of paper: Article
Tentative title: GELATIN AND GLYCERINE-BASED BIOADHESIVE VAGINAL HYDROGEL
Author: Roberta Cassano, Adriana Trapani, Delia Mandracchia, Sonia Trombino
Affiliation: Department of Pharmacy, Health and Nutritional Sciences, Università della Calabria, Arcavacata di Rende, Cosenza, Italy; Department of Pharmacy, Università degli Studi di Bari Aldo, Bari, Italy
Abstract: The aim of this work was the preparation and characterization of an hydrogel based on gelatin and glycerine, useful as a carrier for site specific release of benzydamine, a topical anti-inflammatory drug, able to attenuate the inflammatory process typical of the vaginal infection. The hydrogel obtained has been characterized through electronic scanning microscopy (SEM) and differential scanning calorimetry (DSC). In addition, due to the precursors properties the hydrogel exhibits a relevant mucoadhesive activity. Its swelling degree was assessed by studies conducted at two different pH and at defined time intervals. In particular, phosphate buffers were used at pH 6.6, to mimic the typical conditions of infectious diseases at the vaginal level, and pH 4.6, to simulate the physiological environment. The obtained results revealed that the hydrogel swells well at both pHs. Release studies conducted at both pathological and physiological pHs have shown that benzydamine is released at the level of the vaginal mucosa in a slow and gradual manner. These results supported the hypothesis of the hydrogel use for the site-specific release of benzydamine in the vaginal mucosa.