Special Issue "Novel Aspects of Redox and Antioxidant Signaling"

A special issue of Antioxidants (ISSN 2076-3921).

Deadline for manuscript submissions: 31 January 2019

Special Issue Editors

Guest Editor
Prof. Dr. Yuichiro J. Suzuki

Department of Pharmacology and Physiology, Georgetown University Medical Center, 3900 Reservoir Road NW, Washington, DC 20057, USA
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Interests: antioxidants; cell signaling; oxygen; reactive oxygen species; redox; signal transduction
Guest Editor
Dr. Nataliia V. Shults

Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington DC, USA
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Guest Editor
Dr. Lucia Marcocci

Department of Biochemical Sciences “A. Rossi Fanelli”, Sapienza University of Rome, Rome, Italy
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Special Issue Information

Dear Colleagues,

About 25–30 years ago, the field of reactive oxygen species (ROS) underwent a paradigm shift from molecular oxygen being the double-edged sword to ROS being the double-edged sword. It is now well established that ROS are not merely damaging causing species, but also regulate biological processes including cell signal transduction. The field of redox signaling has emerged, and new and exciting discoveries revealing that ROS and antioxidants regulate various aspects of cell signaling and cellular functions have been made. The Special Issue on "Novel Aspects of Redox and Antioxidant Signaling" seeks to compile recent advances in mechanisms and functions of redox signaling as well as the antioxidant regulation of cellular functions. This Special Issue welcomes the submission of original contribution papers, mini-reviews summarizing work in your laboratory, as well as comprehensive review articles. Some of the topics that will be covered in the Special Issue include:

  • Vitamin E nicotinate signaling
  • Juglone signaling
  • Inhibition of antioxidant pathway of Bcl-2
  • Protein carbonylation and decarbonylation in redox signaling
  • Oxidant-mediated amino acid conversion as a new mechanism of oxidative stress and cell signaling
  • Redox regulation of peroxiredoxins
  • Mitochondria ultrastructure and cell signaling
  • Transmission electron microscopic assessment of mitochondria in oxidative stress and cell signaling
  • Redox signaling in right-sided heart failure
  • Antioxidant regulation of cell reprogramming
Prof. Dr. Yuichiro J. Suzuki

Dr. Nataliia V. Shults
Dr. Lucia Marcocci
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 550 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antioxidants
  • cell signaling
  • oxygen
  • reactive oxygen species
  • redox
  • signal transduction

Published Papers (1 paper)

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Review

Open AccessReview Redox Biology of Right-Sided Heart Failure
Antioxidants 2018, 7(8), 106; https://doi.org/10.3390/antiox7080106
Received: 25 June 2018 / Revised: 21 July 2018 / Accepted: 7 August 2018 / Published: 8 August 2018
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Abstract
Right-sided heart failure is the major cause of death among patients who suffer from various forms of pulmonary hypertension and congenital heart disease. The right ventricle (RV) and left ventricle (LV) originate from different progenitor cells and function against very different blood pressures.
[...] Read more.
Right-sided heart failure is the major cause of death among patients who suffer from various forms of pulmonary hypertension and congenital heart disease. The right ventricle (RV) and left ventricle (LV) originate from different progenitor cells and function against very different blood pressures. However, differences between the RV and LV formed after birth have not been well defined. Work from our laboratory and others has accumulated evidence that redox signaling, oxidative stress and antioxidant regulation are important components that define the RV/LV differences. The present article summarizes the progress in understanding the roles of redox biology in the RV chamber-specificity. Understanding the mechanisms of RV/LV differences should help develop selective therapeutic strategies to help patients who are susceptible to and suffering from right-sided heart failure. Modulations of redox biology may provide effective therapeutic avenues for these conditions. Full article
(This article belongs to the Special Issue Novel Aspects of Redox and Antioxidant Signaling)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

(1) Original Contribution: Vitamin E nicotinate signaling
(2) Original Contribution: Thiol regulation of peroxiredoxin 6
(3) Original Contribution: Effects of the Inhibition of antioxidant pathway of Bcl-2 in pulmonary hypertension
(4) Mini-Review: Effects of juglone on oxidative stress and cell signaling
(5) Mini-Review: Antioxidant regulation of cell reprogramming
(6) Mini-Review: Transmission electron microscopic assessment of mitochondria in oxidative stress and cell signaling
(7) Mini-Review: Redox signaling in right-sided heart failure
(8) Mini-Review: Cell signaling of anaerobic bacteria expose to oxygen
(9) Original Contribution: TBA
(10) Hypothesis Paper: Oxidant-mediated protein amino acid conversion as a new mechanism of oxidative stress and redox signaling
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