Therapeutic Strategies Affecting MAPK-Oriented Interventions in Cancer

Dear Colleagues,

Mitogen-activated protein kinases (MAPKs) are protein kinases that play a key role in the transduction of extracellular signals to cellular responses that has implication in several types of cancer. Their mutated oncogenes turn normal cell phenotypes to become mesenchymal cancerous phenotypes. Therefore, research studies targeting the MAPK signaling and potential development of vaccines against these targets to impact the cancer immune environment are required. Studies involving future applications of immune-targeted vaccines as a cancer therapeutics implementing into clinical research are invited. Therefore, this Special Issue aims to give an overview to develop new strategies involving vaccines to treat cancer at the very early stages to improve survival. In this Special Issue plans to focus on the signaling pathways that can cause malignancy and identify not only chemo-preventive biomarkers but also valid targets for anticancer therapy. Hence, in this Special Issue, we invite and encourage high-quality original research and reviews.

Dr. Sunil Singh
Guest Editor

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• identification of cancer prognostic biomarkers
• vaccines against cancers
• therapeutic strategies
• targets for anticancer therapy
• mechanism of actions
• adverse effects of targeting signaling
• effect on cancer patient’s survival rate