Topical Collection "Heavy Metals Toxicology"
A topical collection in Toxics (ISSN 2305-6304).
Prof. Dr. Wayne Briner
Department of Psychology, Ashford University, 8620 Spectrum Center Blvd, San Diego, CA 92123 USA
Phone: +858 705 2294
Interests: neurotoxicology; heavy metals; teratology; behavioral teratology
Heavy metals such as lead and mercury continue to effect human and environmental health. Heavy metals not only persist in the environment but continue to be produced and released by mining, manufacturing and environmental processes. Human exposure persists and even expands as humankind develops more manufacturing and mining processes, encroaches on more land area, and develops uses for a wider variety of heavy metals. Progress has been made in understanding the toxicology of metals, prevention has been improved and treatment refined over the years. Despite these advances more research needs to be done.
We invite contributors to this collection of Toxics that will focus on heavy metal toxicology. We invite all papers addressing this problem. Theoretical papers will also be considered. We especially encourage papers examining metal-metal interactions and pharmacologic treatment of heavy metal exposure.
Professor Dr. Wayne Briner
Manuscript Submission Information
Manuscripts for the topical collection can be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on this website. The topical collection considers regular research articles, short communications and review articles. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page.
Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- heavy metal
- molecular mechanisms
2014 ( 4 papers )
Toxics 2014, 2(3), 364-376; doi:10.3390/toxics2030364
Received: 21 February 2014; in revised form: 30 May 2014 / Accepted: 18 June 2014 / Published: 25 June 2014| PDF Full-text (485 KB)
Toxics 2014, 2(2), 327-345; doi:10.3390/toxics2020327
Received: 6 May 2014; in revised form: 4 June 2014 / Accepted: 5 June 2014 / Published: 18 June 2014| PDF Full-text (975 KB) | HTML Full-text | XML Full-text
Article: Effects of Lead and Cadmium on Brain Endothelial Cell Survival, Monolayer Permeability, and Crucial Oxidative Stress Markers in an in Vitro Model of the Blood-Brain Barrier
Toxics 2014, 2(2), 258-275; doi:10.3390/toxics2020258
Received: 2 April 2014; in revised form: 26 May 2014 / Accepted: 29 May 2014 / Published: 5 June 2014| PDF Full-text (706 KB) | HTML Full-text | XML Full-text
Toxics 2014, 2(1), 50-78; doi:10.3390/toxics2010050
Received: 14 January 2014; in revised form: 10 February 2014 / Accepted: 20 February 2014 / Published: 17 March 2014| PDF Full-text (877 KB) | HTML Full-text | XML Full-text
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Toxicity of glutathione-binding metals: a review of targets and mechanisms.
Author: Federico M. Rubino
Affiliation: LaTMA – Laboratory for Analytical Toxicology and Metabolomics, Department of Health Sciences, Università degli Studi di Milano @ Ospedale San Paolo, v.Antonio di Rudinì 8, Milano, Italia
Abstract: Mercury, cadmium, arsenic and lead are priority targets for toxicological studies due to the frequent human exposure and to the significant burden of disease following acute and chronic intoxication. Among their common characteristics is chemical affinity to proteins and non-protein thiols and their inability to generate cellular oxidative stress by the best-known Fenton mechanism. Their health effects are however diverse: kidney and liver damage, cancer at specific sites, irreversible neurological damages with metal-specific features. Mechanisms for the induction of oxidative stress by interaction with the cell thiolome will be presented, on the basis of literature evidence and of experimental findings.
Type of Paper: Review
Title: An update and review of unconventional Metals Testing and Treatments
Authors: Stefanos N. Kales, Rose Goldman and Diana Felton
Abstract: Most patients who receive unconventional testing for metals do not have any remarkable exposure history and typically lack symptoms or objective findings compatible with classic heavy metal intoxications.
Unconventional tests results are usually promoted by alternative practitioners as the basis for recommending, promoting, and selling to the patient questionable and often inappropriate therapies/interventions supposedly aimed at "detoxification." Most of these patients will have no evidence of overexposure to metals on the basis of a thorough history and will have levels of metals on conventional tests performed at reliable laboratories that are undetectable or within background ranges for the general population.
Last update: 30 June 2014