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Toxics 2014, 2(3), 364-376; doi:10.3390/toxics2030364
Review

The Alchemist’s Approach to Metal Poisoning: Transforming the Metal Burden

Received: 21 February 2014; in revised form: 30 May 2014 / Accepted: 18 June 2014 / Published: 25 June 2014
(This article belongs to the collection Heavy Metals Toxicology)
Download PDF [485 KB, uploaded 25 June 2014]
Abstract: Metal poisoning is a global problem with humans being exposed to a wide range of metals in varying doses and varying time frames. Traditionally, treatment involves removal of the toxic source or chelation therapy. An intermediate approach is needed. This review outlines the argument for the use of essential metal supplementation as a strategy to induce metallothionein expression and displace the toxic metal from important biological systems, improving the metal burden of the patient. Specific recommendations are given for supplementation with calcium, zinc and vitamin E as a broad strategy to improve the status of those exposed to toxic metals.
Keywords: metal poisoning; treatment; zinc; metallothionein metal poisoning; treatment; zinc; metallothionein
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Briner, W. The Alchemist’s Approach to Metal Poisoning: Transforming the Metal Burden. Toxics 2014, 2, 364-376.

AMA Style

Briner W. The Alchemist’s Approach to Metal Poisoning: Transforming the Metal Burden. Toxics. 2014; 2(3):364-376.

Chicago/Turabian Style

Briner, Wayne. 2014. "The Alchemist’s Approach to Metal Poisoning: Transforming the Metal Burden." Toxics 2, no. 3: 364-376.

Toxics EISSN 2305-6304 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert