Special Issue "Asymmetric Organocatalysis"

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A special issue of Symmetry (ISSN 2073-8994).

Deadline for manuscript submissions: closed (31 March 2011)

Special Issue Editor

Guest Editor
Prof. Dr. Svetlana Tsogoeva
Institut für Organische Chemie I, Friedrich-Alexander Universität Erlangen-Nürnberg, Henkestrasse 42, 91054 Erlangen, Germany
Website: http://www.chemie.uni-erlangen.de/tsogoeva/
E-Mail: tsogoeva@chemie.uni-erlangen.de
Phone: +49 9131 85 22541
Fax: +49 9131 85 26865
Interests: asymmetric organocatalysis and organo-autocatalysis; synthesis of natural product hybrids for medicinal chemistry; redox-active metal complexes for asymmetric oxidation reactions

Special Issue Information

Dear Colleagues,

Evidently, enantiomers of bioactive compounds often have very different and, even opposite pharmacologic effects. Hitherto, many successful strategies were invented by chemists in order to obtain enantiomerically pure drugs and/or their intermediates.

Asymmetric organocatalysis, which is a powerful and environmentally friendly new methodology, facilitates strategies that provide an alternative to the conventional processes, which use transition-metal-complexes.

In many cases, the effectiveness of organocatalysts relies on covalent bonding: e.g. enamine/iminium ion activation by Lewis basic secondary or primary amines, or on the hydrogen bonding interactions: e.g. non-covalent catalysis with ureas and thioureas, diols, etc. Over the past years, a remarkable number of new enantioselective reactions subject to Brønsted- or Lewis-acid catalysis have been identified. Specifically, research has been focused on bi- and multi-functional catalysts containing Lewis or Brønsted basic moieties in combination with additional Lewis/Brønsted acidic functionality or hydrogen bond donors.Another fascinating organocatalytic system uses chiral phase-transfer catalysts (PTC).

Contributions are invited on all types of asymmetric organocatalysis and include:

  • covalent and non-covalent organocatalysis,
  • Lewis- or Brønsted-base organocatalysis,
  • Brønsted- or Lewis-acid organocatalysis,
  • asymmetric PTC,
  • bi- and multi-functional organocatalysis.

Prof. Dr. Svetlana Tsogoeva
Guest Editor

Published Papers (5 papers)

by ,  and
Symmetry 2011, 3(2), 265-282; doi:10.3390/sym3020265
Received: 7 February 2011; in revised form: 23 May 2011 / Accepted: 24 May 2011 / Published: 1 June 2011
Show/Hide Abstract | Cited by 8 | PDF Full-text (330 KB)

by ,  and
Symmetry 2011, 3(2), 220-245; doi:10.3390/sym3020220
Received: 29 March 2011; in revised form: 10 May 2011 / Accepted: 11 May 2011 / Published: 23 May 2011
Show/Hide Abstract | Cited by 17 | PDF Full-text (1519 KB)

by , , ,  and
Symmetry 2011, 3(2), 165-170; doi:10.3390/sym3020165
Received: 10 March 2011; in revised form: 11 April 2011 / Accepted: 12 April 2011 / Published: 20 April 2011
Show/Hide Abstract | Cited by 5 | PDF Full-text (179 KB)
abstract graphic

by , ,  and
Symmetry 2011, 3(2), 155-164; doi:10.3390/sym3020155
Received: 18 February 2011; in revised form: 6 April 2011 / Accepted: 7 April 2011 / Published: 8 April 2011
Show/Hide Abstract | Cited by 7 | PDF Full-text (134 KB)
abstract graphic

by ,  and
Symmetry 2011, 3(1), 84-125; doi:10.3390/sym3010084
Received: 18 February 2011; in revised form: 8 March 2011 / Accepted: 9 March 2011 / Published: 22 March 2011
Show/Hide Abstract | Cited by 15 | PDF Full-text (457 KB)

Last update: 5 March 2014

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