Special Issue "Asymmetric Organocatalysis"
A special issue of Symmetry (ISSN 2073-8994).
Deadline for manuscript submissions: closed (31 March 2011)
Prof. Dr. Svetlana Tsogoeva
Institut für Organische Chemie I, Friedrich-Alexander Universität Erlangen-Nürnberg, Henkestrasse 42, 91054 Erlangen, Germany
Phone: +49 9131 85 22541
Fax: +49 9131 85 26865
Interests: asymmetric organocatalysis and organo-autocatalysis; synthesis of natural product hybrids for medicinal chemistry; redox-active metal complexes for asymmetric oxidation reactions
Evidently, enantiomers of bioactive compounds often have very different and, even opposite pharmacologic effects. Hitherto, many successful strategies were invented by chemists in order to obtain enantiomerically pure drugs and/or their intermediates.
Asymmetric organocatalysis, which is a powerful and environmentally friendly new methodology, facilitates strategies that provide an alternative to the conventional processes, which use transition-metal-complexes.
In many cases, the effectiveness of organocatalysts relies on covalent bonding: e.g. enamine/iminium ion activation by Lewis basic secondary or primary amines, or on the hydrogen bonding interactions: e.g. non-covalent catalysis with ureas and thioureas, diols, etc. Over the past years, a remarkable number of new enantioselective reactions subject to Brønsted- or Lewis-acid catalysis have been identified. Specifically, research has been focused on bi- and multi-functional catalysts containing Lewis or Brønsted basic moieties in combination with additional Lewis/Brønsted acidic functionality or hydrogen bond donors.Another fascinating organocatalytic system uses chiral phase-transfer catalysts (PTC).
Contributions are invited on all types of asymmetric organocatalysis and include:
- covalent and non-covalent organocatalysis,
- Lewis- or Brønsted-base organocatalysis,
- Brønsted- or Lewis-acid organocatalysis,
- asymmetric PTC,
- bi- and multi-functional organocatalysis.
Prof. Dr. Svetlana Tsogoeva
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Symmetry is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 500 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
Symmetry 2011, 3(1), 84-125; doi:10.3390/sym3010084
Received: 18 February 2011; in revised form: 8 March 2011 / Accepted: 9 March 2011 / Published: 22 March 2011| Download PDF Full-text (457 KB)
Article: Primary Amino Acid Lithium Salt-Catalyzed Asymmetric Michael Addition of Carbon Nucleophiles to Enones
Symmetry 2011, 3(2), 155-164; doi:10.3390/sym3020155
Received: 18 February 2011; in revised form: 6 April 2011 / Accepted: 7 April 2011 / Published: 8 April 2011| Download PDF Full-text (134 KB)
Article: Facile and Convenient One-Pot Process for the Synthesis of Spirooxindole Derivatives in High Optical Purity Using (−)-(S)-Brevicolline as an Organocatalyst
Symmetry 2011, 3(2), 165-170; doi:10.3390/sym3020165
Received: 10 March 2011; in revised form: 11 April 2011 / Accepted: 12 April 2011 / Published: 20 April 2011| Download PDF Full-text (179 KB)
Symmetry 2011, 3(2), 220-245; doi:10.3390/sym3020220
Received: 29 March 2011; in revised form: 10 May 2011 / Accepted: 11 May 2011 / Published: 23 May 2011| Download PDF Full-text (1519 KB)
Review: Prolinethioamides versus Prolinamides in Organocatalyzed Aldol Reactions—A Comparative Study
Symmetry 2011, 3(2), 265-282; doi:10.3390/sym3020265
Received: 7 February 2011; in revised form: 23 May 2011 / Accepted: 24 May 2011 / Published: 1 June 2011| Download PDF Full-text (330 KB)
Last update: 5 October 2012