Symmetry 2011, 3(2), 220-245; doi:10.3390/sym3020220
Review

Organocatalytic Enantioselective Henry Reactions

1email, 1email and 1,2,* email
Received: 29 March 2011; in revised form: 10 May 2011 / Accepted: 11 May 2011 / Published: 23 May 2011
(This article belongs to the Special Issue Asymmetric Organocatalysis)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A large number of interesting organocatalytic enantioselective protocols have been explored and successfully applied in the last decade. Among them, the Henry (nitroaldol) reaction represents a powerful carbon-carbon bond-forming procedure for the preparation of valuable synthetic intermediates, such as enantioenriched nitro alcohols, which can be further transformed in a number of important nitrogen and oxygen-containing compounds. This area of research is still in expansion and a more complex version of this useful process has recently emerged, the domino Michael/Henry protocol, affording highly functionalized cycles with multiple stereogenic centers.
Keywords: Henry; nitroaldol; organocatalysis; enantioselective; nitroalkanes; domino Michael/Henry
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MDPI and ACS Style

Alvarez-Casao, Y.; Marques-Lopez, E.; Herrera, R.P. Organocatalytic Enantioselective Henry Reactions. Symmetry 2011, 3, 220-245.

AMA Style

Alvarez-Casao Y, Marques-Lopez E, Herrera RP. Organocatalytic Enantioselective Henry Reactions. Symmetry. 2011; 3(2):220-245.

Chicago/Turabian Style

Alvarez-Casao, Yolanda; Marques-Lopez, Eugenia; Herrera, Raquel P. 2011. "Organocatalytic Enantioselective Henry Reactions." Symmetry 3, no. 2: 220-245.

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