Functional Nanomaterials for Drug Delivery in Photodynamic Therapy
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 186
Special Issue Editors
Interests: photobiology; organic chemistry; photodynamic therapy; biocatalysis; metal nanoparticles; natural exctracts
Special Issues, Collections and Topics in MDPI journals
Interests: photodynamic therapy; drug delivery; photosensitizers; BODIPYs; porphyrins; tumor and cell penetrating peptides; photobiology
Special Issue Information
Dear Colleagues,
In this Special Issue, we aim to provide particular attention to functional nanomaterials for drug delivery in photodynamic therapy (PDT).
PDT is a particularly appealing anticancer approach that relies on the simultaneous presence of three non-toxic components (photosensitizer or PS, light, and molecular oxygen). In the presence of oxygen, only irradiation triggers the production of reactive oxygen species. The intrinsic selectivity of PDT, due to the negligible cytotoxicity in the absence of light and oxygen, has prompted efforts from the scientific community to identify strategies and further enhance the selectivity of PS for cancer cells.
Drug delivery (nano)systems have demonstrated significant potential in increasing the solubility of hydrophobic drugs, improving biodistribution and pharmacokinetics, and allowing preferential accumulation. Thus, over the years, PSs have been conjugated with different nanomaterials to maximize their selectivity/specificity in target cells.
In this Special Issue, we aim to collect research articles and reviews that address the latest advances in using functional nanomaterials for targeted PDT.
We look forward to receiving your contributions.
Dr. Enrico Caruso
Dr. Miryam Chiara Malacarne
Guest Editors
Manuscript Submission Information
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Keywords
- nanomaterials
- drug delivery systems
- photodynamic therapy
- targeted therapies
- third-generation photosensitizers
- targeting agents
